{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:33:03Z","timestamp":1789882383484,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2011,7,11]],"date-time":"2011-07-11T00:00:00Z","timestamp":1310342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2011,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tetraphenylethylene (TPE)\u2010based glycoconjugates were easily synthesized by copper(I)\u2010catalyzed \u201cclick reactions\u201d between propargyl\u2010attached TPE and azido\u2010functionalized sugars. The TPE compound bearing lactosyl moieties (<jats:bold>Lac\u2010TPE<\/jats:bold>) was found to be a fluorescence \u201cturn\u2010on\u201d sensor for cholera toxin by virtue of aggregation\u2010induced emission characteristics of the TPE motif owing to the specific interaction of lactose with the cholera toxin B subunit, whilst a cellobiose\u2010functionalized TPE derivative did not show any response to the toxin. Therefore, <jats:bold>Lac\u2010TPE<\/jats:bold> shows promising applications in the detection of cholera toxin, as well as in the investigation of carbohydrate\u2013protein interaction.<\/jats:p>","DOI":"10.1002\/asia.201100141","type":"journal-article","created":{"date-parts":[[2011,7,11]],"date-time":"2011-07-11T10:16:02Z","timestamp":1310379362000},"page":"2376-2381","source":"Crossref","is-referenced-by-count":65,"title":["Tetraphenylethylene\u2010based Glycoconjugate as a Fluorescence \u201cTurn\u2010On\u201d Sensor for Cholera Toxin"],"prefix":"10.1002","volume":"6","author":[{"given":"Xin\u2010Ming","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Xiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian\u2010Yi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao\u2010Guo","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Jian","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao\u2010Hang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,7,11]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)15328-7"},{"key":"e_1_2_6_2_2","unstructured":"\u00a0"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.1323"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0690(200112)2001:24<4685::AID-EJOC4685>3.0.CO;2-9"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac061462j"},{"key":"e_1_2_6_6_2","unstructured":"\u00a0"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-440X(95)80071-9"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560030202"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0378207"},{"key":"e_1_2_6_10_2","unstructured":"\u00a0"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr940413g"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3757(19981016)110:20<2908::AID-ANGE2908>3.0.CO;2-2"},{"key":"e_1_2_6_12_3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(19981102)37:20<2754::AID-ANIE2754>3.0.CO;2-3"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr0300284"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar00056a001"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr000418f"},{"key":"e_1_2_6_16_2","unstructured":"\u00a0"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1039\/b105159h"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2009.07.153"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/b904665h"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1039\/b921610c"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma8024706"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1039\/B608425G"},{"key":"e_1_2_6_23_2","unstructured":"\u00a0"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.2753723"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol801855s"},{"key":"e_1_2_6_26_2","unstructured":"\u00a0"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/jp073147m"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200701723"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac9002722"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1039\/c002894k"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.02.155"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/asia.200900430"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2010.09.112"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr00097a007"},{"key":"e_1_2_6_35_2","unstructured":"\u00a0"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3757(20010601)113:11<2056::AID-ANGE2056>3.0.CO;2-W"},{"key":"e_1_2_6_36_3","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.0.CO;2-5"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3757(20020715)114:14<2708::AID-ANGE2708>3.0.CO;2-0"},{"key":"e_1_2_6_37_3","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-1992-26175"},{"key":"e_1_2_6_39_2","unstructured":"\u00a0"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2008.06.031"},{"key":"e_1_2_6_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2008.12.035"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/21\/43\/435502"},{"key":"e_1_2_6_43_2","unstructured":"CCDC\u2005825731 (1) contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre viawww.ccdc.cam.ac.uk\/data_request\/cif."}],"container-title":["Chemistry \u2013 An Asian Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fasia.201100141","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/asia.201100141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:37:05Z","timestamp":1759941425000},"score":1,"resource":{"primary":{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/10.1002\/asia.201100141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7,11]]},"references-count":46,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9,5]]}},"alternative-id":["10.1002\/asia.201100141"],"URL":"https:\/\/doi.org\/10.1002\/asia.201100141","archive":["Portico"],"relation":{},"ISSN":["1861-4728","1861-471X"],"issn-type":[{"value":"1861-4728","type":"print"},{"value":"1861-471X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7,11]]}}}