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In our recent report, 2\u2010azaadamantane <jats:italic>N<\/jats:italic>\u2010oxyl (AZADO)\/copper catalysis promoted the highly chemoselective aerobic oxidation of unprotected amino alcohols into amino carbonyl compounds. Herein, we investigated the extension of the promising AZADO\/copper\u2010catalyzed aerobic oxidation of alcohols to other types of alcohol. During close optimization of the reaction conditions by using various alcohols, we found that the optimum combination of nitroxyl radical, copper salt, and solution concentration was dependent on the type of substrate. Various alcohols, including highly hindered and heteroatom\u2010rich ones, were efficiently oxidized into their corresponding carbonyl compounds under mild conditions with lower amounts of the catalysts.<\/jats:p>","DOI":"10.1002\/asia.201403245","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T17:02:08Z","timestamp":1422032528000},"page":"1004-1009","source":"Crossref","is-referenced-by-count":27,"title":["Highly Efficient Aerobic Oxidation of Alcohols by Using Less\u2010Hindered Nitroxyl\u2010Radical\/Copper Catalysis: Optimum Catalyst Combinations and Their Substrate 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