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Although treatment of KO<jats:italic>t<\/jats:italic>Bu with the amine complexes originating from <jats:bold>1\u2009a<\/jats:bold> and <jats:bold>1\u2009a\u2019<\/jats:bold> afforded amido\u2010bridged dinuclear complexes (<jats:bold>3\u2009a<\/jats:bold> and <jats:bold>3\u2009a\u2019<\/jats:bold>), more sterically hindered complexes were solely transformed into the coordinatively unsaturated mononuclear amido complexes (<jats:bold>3\u2009b<\/jats:bold> and <jats:bold>3\u2009c<\/jats:bold>), which can serve as real catalyst species in the asymmetric transfer hydrogenation. The structural difference in the C\u2212N chelate framework markedly affected the catalytic performance. Among them, amido complex\u2005<jats:bold>3\u2009c<\/jats:bold> showed a pronounced ability to catalyze the transfer hydrogenation of acetophenone in 2\u2010propanol, even at a low temperature of \u221230\u2009\u00b0C. A hydridoiridium complex (<jats:bold>4\u2009c<\/jats:bold>) was also identified in the reaction of <jats:bold>3\u2009c<\/jats:bold> in 2\u2010propanol, which provides mechanistic insights into the enantiodiscriminating step in the hydrogen transfer to prochiral ketones.<\/jats:p>","DOI":"10.1002\/asia.201600955","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T09:47:52Z","timestamp":1470217672000},"page":"2924-2931","source":"Crossref","is-referenced-by-count":12,"title":["Comparative Study of Bifunctional Mononuclear and Dinuclear Amidoiridium Complexes with Chiral C\u2212N Chelating Ligands for the Asymmetric Transfer Hydrogenation of Ketones"],"prefix":"10.1002","volume":"11","author":[{"given":"Yasuhiro","family":"Sato","sequence":"first","affiliation":[{"name":"Department of Chemical Science and Engineering, School of Materials and Chemical Technology Tokyo Institute of Technology  2-12-1-E4-1 O-okayama, Meguro-ku Tokyo 152-8552 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