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To achieve their selective and sensitive detection, a novel near\u2010infrared (NIR) fluorescent probe (<jats:bold>CCP\u20101<\/jats:bold>) from a focused library was developed for thiophenol species. Our studies show that <jats:bold>CCP\u20101<\/jats:bold> displays a thiophenol\u2010triggered 28\u2010fold fluorescence intensity enhancement at 706\u2005nm, with a detection limit of 34\u2005n<jats:sc>m<\/jats:sc> observed. It is also able to differentiate thiophenols from various other thiol\u2010containing analytes including hydrogen sulfide, hydrogen persulfide, and aliphatic thiols. In total, the desirable properties (e.g., excitation\/emission in the NIR region, good cell\u2010membrane permeability, intracellular stability, and low cytotoxicity) make <jats:bold>CCP\u20101<\/jats:bold> a potential candidate for thiophenol detection both in vitro and in vivo. In addition, <jats:bold>CCP\u20101<\/jats:bold>, for the first time, successfully visualized thiophenols in mice models of thiophenol inhalation.<\/jats:p>","DOI":"10.1002\/asia.201601309","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T03:52:46Z","timestamp":1477021966000},"page":"3575-3582","source":"Crossref","is-referenced-by-count":34,"title":["A Selective Near\u2010Infrared Fluorescent Probe for In Vivo Imaging of Thiophenols from a Focused Library"],"prefix":"10.1002","volume":"11","author":[{"given":"Yue","family":"Pan","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemo\/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University  Changsha, Hunan 410082 P.R. 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