{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T10:22:07Z","timestamp":1790158927920,"version":"4.1.0"},"reference-count":137,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T00:00:00Z","timestamp":1499731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2017,8,17]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>It is well established that the majority of chlorinated organic substances found in the terrestrial environment are produced naturally. The presence of these compounds in soils is not limited to a single ecosystem. Natural chlorination is also a widespread phenomenon in grasslands and agricultural soils typical for unforested areas. These chlorinated compounds are formed from chlorination of natural organic matter consisting of very complex chemical structures, such as lignin. Chlorination of several lignin model compounds results in the intermediate formation of trichloroacetyl\u2010containing compounds, which are also found in soils. These decay, in general, through a haloform\u2010type reaction mechanism to CHCl<jats:sub>3<\/jats:sub>. Upon release into the atmosphere, CHCl<jats:sub>3<\/jats:sub> will produce chlorine radicals through photolysis, which will, in turn, lead to natural depletion of ozone. There is evidence that fungal chloroperoxidases able to produce HOCl are involved in the chlorination of natural organic matter. The objective of this review is to clarify the role and source of the various chloroperoxidases involved in the natural formation of CHCl<jats:sub>3<\/jats:sub>.<\/jats:p>","DOI":"10.1002\/asia.201700420","type":"journal-article","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T05:22:53Z","timestamp":1496294573000},"page":"1997-2007","source":"Crossref","is-referenced-by-count":39,"title":["Vanadium Chloroperoxidases: The Missing Link in the Formation of Chlorinated Compounds and Chloroform in the Terrestrial Environment?"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3683-2821","authenticated-orcid":false,"given":"Ron","family":"Wever","sequence":"first","affiliation":[{"name":"Van't Hoff Institute for Molecular Sciences University of Amsterdam  Science Park 904 1098 XH Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil","family":"Barnett","sequence":"additional","affiliation":[{"name":"Department of Anatomy Embryology and Physiology Academic Medical Center Amsterdam  Meibergdreef 15 1105 AZ Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,11]]},"reference":[{"key":"e_1_2_6_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2015.02.013"},{"key":"e_1_2_6_2_1","unstructured":"\u00a0"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3dt50525a"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4MT00304G"},{"key":"e_1_2_6_5_1","unstructured":"\u00a0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-008-0090-4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-49875-0_2"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/es00110a005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(98)00487-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apgeochem.2010.08.003"},{"key":"e_1_2_6_11_1","unstructured":"\u00a0"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2010.09.008"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1039\/B920932H"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2012.07.058"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gca.2013.09.028"},{"key":"e_1_2_6_16_1","unstructured":"\u00a0"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/es980127c"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(98)00487-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1352-2310(00)00285-5"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/es00170a009"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/es00081a005"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10533-012-9771-7"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.5194\/bg-3-167-2006"},{"key":"e_1_2_6_24_1","unstructured":"\u00a0"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10533-016-0241-5"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1029\/2008GL035762"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/es501810g"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1071\/EN14202"},{"key":"e_1_2_6_29_1","unstructured":"\u00a0"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apgeochem.2010.08.003"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2014.05.080"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(00)00044-8"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1021\/es8035779"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/es8032605"},{"key":"e_1_2_6_35_1","unstructured":"\u00a0"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2009.01915.x"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2012.02807.x"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0038-0717(93)90239-8"},{"key":"e_1_2_6_39_1","first-page":"3709","author":"Laturnus F.","year":"1995","journal-title":"Chemosphere"},{"key":"e_1_2_6_40_1","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/S0021-9258(19)63275-8","volume":"236","author":"Shaw P. D.","year":"1961","journal-title":"J. Biol. Chem."},{"key":"e_1_2_6_41_1","first-page":"28958","author":"Weigold P.","journal-title":"Sci. Rep."},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0610074104"},{"key":"e_1_2_6_43_1","unstructured":"\u00a0"},{"key":"e_1_2_6_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199114871"},{"key":"e_1_2_6_44_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.19911031141"},{"key":"e_1_2_6_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0894-532"},{"key":"e_1_2_6_46_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.1802"},{"key":"e_1_2_6_47_1","unstructured":"\u00a0"},{"key":"e_1_2_6_48_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1116510"},{"key":"e_1_2_6_49_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi0621213"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201509573"},{"key":"e_1_2_6_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201509573"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/es303343u"},{"key":"e_1_2_6_52_1","unstructured":"\u00a0"},{"key":"e_1_2_6_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature04544"},{"key":"e_1_2_6_54_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja8097355"},{"key":"e_1_2_6_55_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006738107"},{"key":"e_1_2_6_56_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr050313i"},{"key":"e_1_2_6_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2112"},{"key":"e_1_2_6_58_1","unstructured":"\u00a0"},{"key":"e_1_2_6_59_2","doi-asserted-by":"crossref","first-page":"2560","DOI":"10.1016\/S0021-9258(18)69738-8","volume":"234","author":"Shaw P. D.","year":"1959","journal-title":"J. Biol. Chem."},{"key":"e_1_2_6_60_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj0340664"},{"key":"e_1_2_6_61_1","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1016\/S0021-9258(19)63275-8","volume":"236","author":"Shaw P. D.","year":"1961","journal-title":"J. Biol. Chem."},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)96701-3"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)96702-5"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)63032-7"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi7022656"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1139\/m88-175"},{"key":"e_1_2_6_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/es0347336"},{"key":"e_1_2_6_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/es403879e"},{"key":"e_1_2_6_69_1","unstructured":"\u00a0"},{"key":"e_1_2_6_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(98)00272-0"},{"key":"e_1_2_6_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0038-0717(99)00069-3"},{"key":"e_1_2_6_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(97)00984-9"},{"key":"e_1_2_6_73_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1067153"},{"key":"e_1_2_6_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/0045-6535(95)00107-J"},{"key":"e_1_2_6_75_1","first-page":"14","volume-title":"Naturally Produced Organohalogens","author":"Hoekstra E. J.","year":"1995"},{"key":"e_1_2_6_76_1","unstructured":"\u00a0"},{"key":"e_1_2_6_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.70.8.4575-4581.2004"},{"key":"e_1_2_6_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2005.10.014"},{"key":"e_1_2_6_79_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-010-2633-0"},{"key":"e_1_2_6_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2014.01.015"},{"key":"e_1_2_6_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201302137"},{"key":"e_1_2_6_81_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201302137"},{"key":"e_1_2_6_82_1","doi-asserted-by":"publisher","DOI":"10.1186\/2191-0855-1-31"},{"key":"e_1_2_6_83_1","first-page":"9","volume-title":"Peroxidases and Catalases","author":"Dunford H. B.","year":"2010"},{"key":"e_1_2_6_84_1","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1997.0217"},{"key":"e_1_2_6_85_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00159a017"},{"key":"e_1_2_6_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0141-0229(99)00180-5"},{"key":"e_1_2_6_87_1","unstructured":"\u00a0"},{"key":"e_1_2_6_88_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M405305200"},{"key":"e_1_2_6_89_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2002.02871.x"},{"key":"e_1_2_6_90_1","doi-asserted-by":"publisher","DOI":"10.1021\/es505464k"},{"key":"e_1_2_6_91_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj2480277"},{"key":"e_1_2_6_92_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/978-94-007-0913-3_5","volume-title":"Vanadium Biochemical and Molecular Biological Approaches","author":"Wever R.","year":"2012"},{"key":"e_1_2_6_93_1","unstructured":"\u00a0"},{"key":"e_1_2_6_94_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja201088k"},{"key":"e_1_2_6_95_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611046200"},{"key":"e_1_2_6_96_1","unstructured":"\u00a0"},{"key":"e_1_2_6_97_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja305665f"},{"key":"e_1_2_6_98_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201405696"},{"key":"e_1_2_6_98_3","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201405696"},{"key":"e_1_2_6_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02153227"},{"key":"e_1_2_6_100_1","unstructured":"J.Geigert T-N. E.Liu T.N'timkulu US 4 707 446 1987."},{"key":"e_1_2_6_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(87)90277-4"},{"key":"e_1_2_6_102_1","doi-asserted-by":"crossref","unstructured":"J. C.Hunter A.Belt L. S.Soto M. E.Fonda US 4 937 192 1990.","DOI":"10.1136\/bmj.301.6757.937-a"},{"key":"e_1_2_6_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(93)90221-C"},{"key":"e_1_2_6_104_1","doi-asserted-by":"publisher","DOI":"10.1042\/bst0230267"},{"key":"e_1_2_6_105_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.36.23381"},{"key":"e_1_2_6_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2002.tb11465.x"},{"key":"e_1_2_6_107_1","unstructured":"The Peroxidase database:http:\/\/peroxibase.toulouse.inra.fr."},{"key":"e_1_2_6_108_1","first-page":"161","volume":"4","author":"Ashok G.","year":"2015","journal-title":"Int. J. Curr. Microbiol. Appl. Sci."},{"key":"e_1_2_6_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02876594"},{"key":"e_1_2_6_110_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13225-014-0298-1"},{"key":"e_1_2_6_111_1","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS-09-11-0772-PDN"},{"key":"e_1_2_6_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-179501-6.50020-X"},{"key":"e_1_2_6_113_1","first-page":"393","volume-title":"Fundamentals of the Fungi","author":"Moore-Landecker E.","year":"1990"},{"key":"e_1_2_6_114_1","doi-asserted-by":"publisher","DOI":"10.3390\/i7090346"},{"key":"e_1_2_6_115_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.1.392"},{"key":"e_1_2_6_116_1","first-page":"1417","volume-title":"Handbook of Metalloproteins","author":"Wever R.","year":"2001"},{"key":"e_1_2_6_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2010.02.007"},{"key":"e_1_2_6_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1994.00151.x"},{"key":"e_1_2_6_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcatb.2008.05.014"},{"key":"e_1_2_6_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.200303008"},{"key":"e_1_2_6_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2004.02.001"},{"key":"e_1_2_6_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199101481"},{"key":"e_1_2_6_122_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.19911030206"},{"key":"e_1_2_6_123_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi9921790"},{"key":"e_1_2_6_124_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.24.11281"},{"key":"e_1_2_6_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4781(96)00238-2"},{"key":"e_1_2_6_126_1","unstructured":"P. Barnett Ph.D. thesis University of Amsterdam 1997."},{"key":"e_1_2_6_127_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.55.031903.141701"},{"key":"e_1_2_6_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(93)80394-A"},{"key":"e_1_2_6_129_1","first-page":"4021","volume":"24","author":"Leri A. C.","year":"2010","journal-title":"Global Biogeochem. Cycles"},{"key":"e_1_2_6_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gca.2007.09.001"},{"key":"e_1_2_6_131_1","doi-asserted-by":"crossref","unstructured":"P. Chomnunti S. Hongsanan B. Aguirre-Hudson Q. Tian D. Persoh M.\u2005K. Dhami A.\u2005S. Alias J. Xu X. Liu M. Stadler K.\u2005D. Hyde Fungal Diversity2014 66 1\u201336.","DOI":"10.1007\/s13225-014-0278-5"},{"key":"e_1_2_6_132_1","doi-asserted-by":"publisher","DOI":"10.1029\/1999JB900369"}],"container-title":["Chemistry \u2013 An Asian Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fasia.201700420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/asia.201700420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:44:13Z","timestamp":1759927453000},"score":1,"resource":{"primary":{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/10.1002\/asia.201700420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,11]]},"references-count":137,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2017,8,17]]}},"alternative-id":["10.1002\/asia.201700420"],"URL":"https:\/\/doi.org\/10.1002\/asia.201700420","archive":["Portico"],"relation":{},"ISSN":["1861-4728","1861-471X"],"issn-type":[{"value":"1861-4728","type":"print"},{"value":"1861-471X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,11]]}}}