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A series of novel highly substituted 3\u2010functionalized 2\u2010aminopyridines were produced in good yields. Reaction mechanism studies, which included control experiments and density\u2010functional theory (DFT) calculations, demonstrated that Rh and potassium carbonate played key roles in the cyclization step.<\/jats:p>","DOI":"10.1002\/asia.202200083","type":"journal-article","created":{"date-parts":[[2022,3,12]],"date-time":"2022-03-12T01:19:23Z","timestamp":1647047963000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Synthesis of Highly Substituted 2\u2010Aminopyridines with Vinyl Azides, Isonitriles, and Ketones"],"prefix":"10.1002","volume":"17","author":[{"given":"Wenxu","family":"Chang","sequence":"first","affiliation":[{"name":"College of Agronomy and Biotechnology and College of Science China Agricultural University  Beijing 100193 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zongyang","family":"Li","sequence":"additional","affiliation":[{"name":"College of Agronomy and Biotechnology and College of Science China Agricultural University  Beijing 100193 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenhui","family":"Yuan","sequence":"additional","affiliation":[{"name":"College of Agronomy and Biotechnology and College of Science China Agricultural University  Beijing 100193 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinying","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Agronomy and Biotechnology and College of Science China Agricultural University  Beijing 100193 P. R. 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6579-1670","authenticated-orcid":false,"given":"Zhenhua","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Agronomy and Biotechnology and College of Science China Agricultural University  Beijing 100193 P. R. 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