{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T21:28:13Z","timestamp":1783114093918,"version":"3.54.6"},"reference-count":92,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T00:00:00Z","timestamp":1664150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006464","name":"Birla Institute of Technology and Science, Pilani","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006464","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aces.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2022,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This report describes the synthesis of two ruthenium(II) ENE pincer complexes (E = S, <jats:bold>C1<\/jats:bold> and E = Se, <jats:bold>C2<\/jats:bold>) by the reaction of bis(2\u2010(phenylchalcogenyl)ethyl)amine (<jats:bold>L1<\/jats:bold>, <jats:bold>L2<\/jats:bold>) with RuCl<jats:sub>2<\/jats:sub>(PPh<jats:sub>3<\/jats:sub>)<jats:sub>3<\/jats:sub>. The complexes were characterized with the help of <jats:sup>1<\/jats:sup>H and <jats:sup>13<\/jats:sup>C{<jats:sup>1<\/jats:sup>H} NMR, FTIR, HRMS, cyclic voltammetry and elemental analysis techniques. The structure and bonding mode of ligand with ruthenium in <jats:bold>C2<\/jats:bold> was established with the help of single crystal X\u2010ray diffraction. The complex showed distorted octahedral geometry with two chlorine atoms <jats:italic>trans<\/jats:italic> to each other. The Ru\u2212Se bond distances (\u00c5) are 2.4564(3)\u20102.4630(3), Ru\u2212N distance is 2.181(2), Ru\u2212P distance is 2.2999(6), and Ru\u2212Cl distances are 2.4078(6)\u20102.4314(6). The complexes showed good to excellent catalytic activity for the <jats:italic>N<\/jats:italic>\u2010alkylation of <jats:italic>o<\/jats:italic>\u2010phenylenediamine with benzyl alcohol derivatives to synthesize 1,2\u2010disubstituted benzimidazole derivatives. The complexes were also found to be efficient for aerobic oxidation of benzyl alcohols to corresponding aldehydes which are precursors to the bisimines generated in\u2005situ during the synthesis of 1,2\u2010disubstituted benzimidazole derivatives. Complex <jats:bold>C2<\/jats:bold> where selenium is coordinated with ruthenium was found to be more efficient as compared to sulfur coordinated ruthenium complex <jats:bold>C1<\/jats:bold>. Since ruthenium complexes are getting increasing attention for developing new anticancer agents, the preliminary studies like binding behavior of both the complexes towards CT\u2010DNA were studied by competitive binding with ethidium bromide (EthBr) using emission spectroscopy. In addition, the interactions of <jats:bold>C1\u2212C2<\/jats:bold> were also studied with bovine serum albumin (BSA) using steady state fluorescence quenching and synchronous fluorescence studies. A good stability of Ru(II) state was observed by cyclic voltammetric studies of <jats:bold>C1\u2212C2<\/jats:bold>. Overall these molecules are good examples of bio\u2010organometallic systems for catalytic and biological applications.<\/jats:p>","DOI":"10.1002\/asia.202200736","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T01:11:44Z","timestamp":1662426704000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Design and Syntheses of Ruthenium ENE (E = S, Se) Pincer Complexes: A Versatile System for Catalytic and Biological Applications"],"prefix":"10.1002","volume":"17","author":[{"given":"Surabhi","family":"Bhatt","sequence":"first","affiliation":[{"name":"ISC Laboratory, Department of Chemistry, School of Chemical Sciences and Pharmacy Central University of Rajasthan, NH-8, Bandarsindri, Ajmer  Rajasthan 305817 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Chemistry Birla 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