{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T19:05:11Z","timestamp":1785179111144,"version":"3.55.0"},"reference-count":122,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T00:00:00Z","timestamp":1733875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aces.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2025,2,17]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The bidentate N, N, donor phenyl\u2010azo\u2010naphthaldoxime NpLH, <jats:bold>1<\/jats:bold> was used to synthesize the ruthenium(II) complex trans\u2010[Ru(NpL)(CO)Cl(PPh<jats:sub>3<\/jats:sub>)<jats:sub>2<\/jats:sub>], <jats:bold>2<\/jats:bold>. It has been characterized by SCXRD, electrochemical and spectral studies. Computational analysis indicates that the low\u2010lying \u03c0*\u2010LUMO of the complex has substantial azo\u2010character of coordinated ligand. This property has been exploited to form an efficient electron transfer pre\u2010catalyst to effectuate dehydrogenative functionalization of a large number of benzyl alcohols to quinazolin\u20104(3H)\u2010ones via condensation with diverse o\u2010amino benzamides as well as N\u2010substituted benzamides under aerobic conditions (57 entries). A reaction mechanism has been projected via isolation of intermediates and certain control experiments. Furthermore, it has been substantiated by theoretical scrutiny using density functional theory (DFT) calculation. The catalytic cycle involves stepwise hydrogen atom transfer (HAT) from benzyl alcohols to the N<jats:sub>azo<\/jats:sub> atoms of the coordinated ligand with subsequent removal of the H\u2010atoms from the N<jats:sub>azo<\/jats:sub> atoms to regenerate the active catalyst.<\/jats:p>","DOI":"10.1002\/asia.202401278","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T02:00:48Z","timestamp":1732845648000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Dehydrogenative Coupling for Synthesis of Quinazolin\u20104(3H)\u2010ones <i>via<\/i> Tandem Reaction using Ruthenium(II)\u2010Phenyl\u2010Azo\u2010Naphthaldoxime: An Experimental and Theoretical Investigation"],"prefix":"10.1002","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8214-3897","authenticated-orcid":false,"given":"Supriyo","family":"Halder","sequence":"first","affiliation":[{"name":"Department of Chemistry Jadavpur University  Kolkata 700032 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2750-9822","authenticated-orcid":false,"given":"Srijita","family":"Naskar","sequence":"additional","affiliation":[{"name":"Department of Chemistry Jadavpur University  Kolkata 700032 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8209-2491","authenticated-orcid":false,"given":"Debashis","family":"Jana","sequence":"additional","affiliation":[{"name":"Department of Chemistry Jadavpur University  Kolkata 700032 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopal","family":"Kanrar","sequence":"additional","affiliation":[{"name":"Department of Chemistry St. Xavier's College (Autonomous)  Kolkata 700016 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyama Charan","family":"Mandal","sequence":"additional","affiliation":[{"name":"SUNCAT Center for Interface Science and Catalysis SLAC National Accelerator Laboratory  2575 Sand Hill Road Menlo Park CA 94025 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0097-6113","authenticated-orcid":false,"given":"Subhadip","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Chemistry The ICFAI University Tripura  Agartala Tripura 799210 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishchal","family":"Bharadwaj","sequence":"additional","affiliation":[{"name":"Department of Chemistry Indian Institute of Technology (IIT) Indore  Indore Madhya Pradesh 453552"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6377-5768","authenticated-orcid":false,"given":"Kausikisankar","family":"Pramanik","sequence":"additional","affiliation":[{"name":"Department of Chemistry Jadavpur University  Kolkata 700032 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6238-7368","authenticated-orcid":false,"given":"Sanjib","family":"Ganguly","sequence":"additional","affiliation":[{"name":"Department of Chemistry St. Xavier's College (Autonomous)  Kolkata 700016 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,11]]},"reference":[{"key":"e_1_2_8_1_1","unstructured":"\u00a0"},{"key":"e_1_2_8_2_2","volume-title":"Comprehensive Heterocyclic Chemistry II. Eds","author":"Katritzky A. R.","year":"1996"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.3987\/COM-97-S65"},{"key":"e_1_2_8_4_2","volume-title":"Heterocyclic Chemistry","author":"Joule J. A.","year":"2010"},{"key":"e_1_2_8_5_2","first-page":"141","volume":"9","author":"Al-Mulla A. A.","year":"2017","journal-title":"PharmaChem"},{"key":"e_1_2_8_6_1","unstructured":"Reviews on quinazolinone alkaloid:"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1039\/b208140g"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1039\/b310691h"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2005.07.010"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1039\/b413750g"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2006.07.098"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA00351A"},{"key":"e_1_2_8_13_1","unstructured":"\u00a0"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.02.005"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1515\/hc-2014-0181"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB01379H"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.10.084"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.21466"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-91095-8.00005-2"},{"key":"e_1_2_8_20_1","unstructured":"\u00a0"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2007.00548.x"},{"key":"e_1_2_8_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2016.06.026"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmcr.2022.100087"},{"key":"e_1_2_8_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.4382"},{"key":"e_1_2_8_25_1","unstructured":"\u00a0"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2020.10.039"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.30574\/gscbps.2020.11.1.0110"},{"key":"e_1_2_8_28_2","doi-asserted-by":"publisher","DOI":"10.21276\/apjhs.2021.8.2.12"},{"key":"e_1_2_8_29_1","unstructured":"\u00a0"},{"key":"e_1_2_8_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2017.03.042"},{"key":"e_1_2_8_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.03.038"},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2019.127097"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25204780"},{"key":"e_1_2_8_34_1","unstructured":"\u00a0"},{"key":"e_1_2_8_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.02.002"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01474"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2019.107832"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113609"},{"key":"e_1_2_8_39_1","unstructured":"\u00a0"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.03.007"},{"key":"e_1_2_8_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2014.03.008"},{"key":"e_1_2_8_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2015.04.009"},{"key":"e_1_2_8_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2022.107111"},{"key":"e_1_2_8_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2023.175829"},{"key":"e_1_2_8_45_1","unstructured":"\u00a0"},{"key":"e_1_2_8_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.02.009"},{"key":"e_1_2_8_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2017.02.012"},{"key":"e_1_2_8_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2018.10.028"},{"key":"e_1_2_8_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113979"},{"key":"e_1_2_8_50_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.3c00891"},{"key":"e_1_2_8_51_1","unstructured":"\u00a0"},{"key":"e_1_2_8_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2016.02.009"},{"key":"e_1_2_8_53_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2021.1972992"},{"key":"e_1_2_8_54_2","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2022.969559"},{"key":"e_1_2_8_55_2","doi-asserted-by":"publisher","DOI":"10.3390\/scipharm91020018"},{"key":"e_1_2_8_56_1","unstructured":"\u00a0"},{"key":"e_1_2_8_57_2","doi-asserted-by":"publisher","DOI":"10.1021\/ol403631k"},{"key":"e_1_2_8_58_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b03446"},{"key":"e_1_2_8_59_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c06827"},{"key":"e_1_2_8_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.202001219"},{"key":"e_1_2_8_61_1","unstructured":"\u00a0"},{"key":"e_1_2_8_62_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1338521"},{"key":"e_1_2_8_63_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00467"},{"key":"e_1_2_8_64_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.6b00249"},{"key":"e_1_2_8_65_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b02334"},{"key":"e_1_2_8_66_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.8b01675"},{"key":"e_1_2_8_67_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c01927"},{"key":"e_1_2_8_68_1","unstructured":"\u00a0"},{"key":"e_1_2_8_69_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.9b01343"},{"key":"e_1_2_8_70_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0DT00394H"},{"key":"e_1_2_8_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2021.132479"},{"key":"e_1_2_8_72_2","doi-asserted-by":"publisher","DOI":"10.1039\/D2CY00260D"},{"key":"e_1_2_8_73_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c02579"},{"key":"e_1_2_8_74_1","unstructured":"\u00a0"},{"key":"e_1_2_8_75_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo301282n"},{"key":"e_1_2_8_76_2","doi-asserted-by":"publisher","DOI":"10.1039\/C1OB06516E"},{"key":"e_1_2_8_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcat.2018.06.007"},{"key":"e_1_2_8_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2017.11.060"},{"key":"e_1_2_8_79_2","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201800660"},{"key":"e_1_2_8_80_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajoc.202200675"},{"key":"e_1_2_8_81_1","unstructured":"\u00a0"},{"key":"e_1_2_8_82_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo201054k"},{"key":"e_1_2_8_83_2","doi-asserted-by":"publisher","DOI":"10.1039\/C5QO00255A"},{"key":"e_1_2_8_84_1","unstructured":"\u00a0"},{"key":"e_1_2_8_85_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.5b02185"},{"key":"e_1_2_8_86_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.7b01514"},{"key":"e_1_2_8_87_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9NJ05527D"},{"key":"e_1_2_8_88_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.0c00240"},{"key":"e_1_2_8_89_2","doi-asserted-by":"publisher","DOI":"10.1039\/D2DT00345G"},{"key":"e_1_2_8_90_2","doi-asserted-by":"publisher","DOI":"10.1039\/D4NJ00391H"},{"key":"e_1_2_8_91_1","unstructured":"\u00a0"},{"key":"e_1_2_8_92_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00123"},{"key":"e_1_2_8_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2020.213241"},{"key":"e_1_2_8_94_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.2c00311"},{"key":"e_1_2_8_95_2","doi-asserted-by":"publisher","DOI":"10.1039\/D3DT02567E"},{"key":"e_1_2_8_96_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.4c00086"},{"key":"e_1_2_8_97_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c02657"},{"key":"e_1_2_8_98_1","unstructured":"\u00a0"},{"key":"e_1_2_8_99_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO00023A"},{"key":"e_1_2_8_100_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.9b00207"},{"key":"e_1_2_8_101_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2021.213967"},{"key":"e_1_2_8_102_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.1c00714"},{"key":"e_1_2_8_103_2","doi-asserted-by":"publisher","DOI":"10.1039\/D0QO01577F"},{"key":"e_1_2_8_104_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.organomet.3c00034"},{"key":"e_1_2_8_105_2","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202301558"},{"key":"e_1_2_8_106_1","unstructured":"\u00a0"},{"key":"e_1_2_8_107_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO00764K"},{"key":"e_1_2_8_108_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajoc.202100034"},{"key":"e_1_2_8_109_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcat.2022.02.018"},{"key":"e_1_2_8_110_2","doi-asserted-by":"publisher","DOI":"10.1039\/D2DT01060G"},{"key":"e_1_2_8_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2021.214257"},{"key":"e_1_2_8_112_1","unstructured":"\u00a0"},{"key":"e_1_2_8_113_2","doi-asserted-by":"publisher","DOI":"10.1021\/ic50068a011"},{"key":"e_1_2_8_114_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo00832a027"},{"key":"e_1_2_8_115_1","unstructured":"\u00a0"},{"key":"e_1_2_8_116_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.6b01310"},{"key":"e_1_2_8_117_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.7b02238"},{"key":"e_1_2_8_118_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.8b01558"},{"key":"e_1_2_8_119_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.9b01343"},{"key":"e_1_2_8_120_1","unstructured":"\u00a0"},{"key":"e_1_2_8_121_2","doi-asserted-by":"publisher","DOI":"10.1039\/C8CP06714G"},{"key":"e_1_2_8_122_2","doi-asserted-by":"publisher","DOI":"10.1002\/cphc.201900862"}],"container-title":["Chemistry \u2013 An Asian Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/asia.202401278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T18:44:31Z","timestamp":1759949071000},"score":1,"resource":{"primary":{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/10.1002\/asia.202401278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,11]]},"references-count":122,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,2,17]]}},"alternative-id":["10.1002\/asia.202401278"],"URL":"https:\/\/doi.org\/10.1002\/asia.202401278","archive":["Portico"],"relation":{},"ISSN":["1861-4728","1861-471X"],"issn-type":[{"value":"1861-4728","type":"print"},{"value":"1861-471X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,11]]},"assertion":[{"value":"2024-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e202401278"}}