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Herein, we report a transition\u2010metal\u2010free photocatalytic protocol for the defluorinative carboxylation, esterification, and amidation of <jats:italic>gem<\/jats:italic>\u2010difluoroarylalkenes with diverse nucleophiles to access a variety of <jats:italic>\u03b1<\/jats:italic>\u2010arylated carboxylic acids, esters, and amides. The strategy features operational simplicity, mild reaction conditions, and excellent substrate compatibility, providing efficient access to pharmaceutically relevant architectures.<\/jats:p>","DOI":"10.1002\/asia.70212","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T15:38:33Z","timestamp":1753717113000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Photoredox\u2010catalyzed Divergent Defluorofunctionalizations of <i>gem<\/i>\u2010difluoroarylalkenes with Nucleophiles to Access <i>\u03b1<\/i>\u2010arylated Carboxylic Acids and its Derivatives"],"prefix":"10.1002","volume":"20","author":[{"given":"Ting\u2010Ting","family":"Miao","sequence":"first","affiliation":[{"name":"College of Chemistry and Chemical Engineering, and Key (Guangdong\u2010Hong Kong Joint) Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province Shantou University  Shantou 515063 P. 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