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Here, we investigate nanocrystalline Faujasite (NanoFAU) and its ion\u2010exchanged derivatives to elucidate how extra\u2010framework cation identity governs the balance between hemostatic and antimicrobial performance. NanoFAU samples exchanged with Ag\n                    <jats:sup>+<\/jats:sup>\n                    , Ba\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , Ca\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    , and Mg\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    were comprehensively characterized by XRD, SEM\/HRTEM\/EDS, AFM, BET surface area analysis,\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>9<\/jats:sup>\n                    Si MAS NMR and FT\u2010IR spectroscopy, confirming preservation of the FAU framework and successful cation substitution. All ion\u2010exchanged materials exhibited isoelectric points below physiological blood pH, consistent with negatively charged, procoagulant surfaces. Thromboelastography revealed that Ca\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    \u2010exchanged NanoFAU (NanoFAU\u2010Ca) achieved the most pronounced hemostatic response (\n                    <jats:italic>R<\/jats:italic>\n                    \u00a0=\u00a01.1\u00a0min;\n                    <jats:italic>K<\/jats:italic>\n                    \u00a0=\u00a01.2\u00a0min; MA\u00a0=\u00a060.3\u00a0mm), whereas Ag\n                    <jats:sup>+<\/jats:sup>\n                    \u2010exchanged NanoFAU (NanoFAU\u2010Ag) provided strong antimicrobial activity against\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (ATCC 25923) and\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    (ATCC 90028), displaying bactericidal and fungistatic effects, respectively. Importantly, NanoFAU\u2010Ag maintained cell viability above the ISO 10993\u20105 cytotoxicity threshold in HaCaT keratinocytes. These findings demonstrate that ion exchange enables rational tuning of NanoFAU to achieve complementary hemostatic and antimicrobial functionalities while preserving cytocompatibility, establishing NanoFAU as a versatile inorganic platform for multifunctional wound management and supporting future in vivo evaluation.\n                  <\/jats:p>","DOI":"10.1002\/asia.70755","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:29:42Z","timestamp":1777523382000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Nanometric Faujasite (FAU) Zeolite Ion\u2010Exchanged With Metal Ions for Hemostatic and Antimicrobial Applications: A Thromboelastographic and Microbiological Study"],"prefix":"10.1002","volume":"21","author":[{"given":"Guilherme de Paula","family":"Guarnieri","sequence":"first","affiliation":[{"name":"Department of Physics S\u00e3o Paulo State University  S\u00e3o Jos\u00e9 do Rio Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Bergamasco","family":"Laurenti","sequence":"additional","affiliation":[{"name":"Department of Physics S\u00e3o Paulo State University  S\u00e3o Jos\u00e9 do Rio Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatriz","family":"Crespo","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology Faculty of Medicine of S\u00e3o Jos\u00e9 Do Rio Preto  S\u00e3o Jos\u00e9 do Rio Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edivandra Buzato","family":"Silva","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology Faculty of Medicine of S\u00e3o Jos\u00e9 Do Rio Preto  S\u00e3o Jos\u00e9 do Rio Preto S\u00e3o Paulo 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