{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T10:55:13Z","timestamp":1789469713822,"version":"build-2803163510"},"reference-count":80,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T00:00:00Z","timestamp":1781395200000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aces.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Chemistry \u0097 An Asian Journal"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Multifunctional fluorescent chemosensors capable of detecting chemically diverse analytes using a single molecular platform are increasingly valuable for environmental monitoring and biomedical analysis due to reducing analytical cost, time, and complexity. However, most Schiff base probes are limited to single\u2010analyte detection or operate through a single sensing mechanism. In this study, a new Schiff base probe,\n                    <jats:bold>ClSNP<\/jats:bold>\n                    , synthesized from 3,5\u2010dichlorosalicylaldehyde and N\u2010phenyl\u2010o\u2010phenylenediamine, exhibited a fluorescence \u201cturn\u2010off\u201d response toward Cu\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    and Co\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    ions in a CH\n                    <jats:sub>3<\/jats:sub>\n                    CN\/H\n                    <jats:sub>2<\/jats:sub>\n                    O medium with high selectivity even in the presence of competing metal ions. Job's plot analysis confirmed a 1:1 binding stoichiometry, with detection limits of 1.79 and 3.40\u00a0\u00b5M for Cu\n                    <jats:sup>2<\/jats:sup>\n                    <jats:sup>+<\/jats:sup>\n                    and Co\n                    <jats:sup>2+<\/jats:sup>\n                    ions, respectively, both below WHO\u2010permitted levels. Additionally, it selectively detected picric acid (PA) in THF with a detection limit of 2.49\u00a0\u00b5M and responded to antibiotics, including nitrofurantoin and metronidazole. It showed a \u201cturn\u2010on\u201d fluorescence enhancement at 460\u00a0nm upon binding with bovine serum albumin (BSA) with a detection limit of 1.28\u00a0\u00b5M, attributed to restricted intramolecular rotation, supported by a molecular docking study. The probe demonstrated high sensitivity, good selectivity, and real\u2010sample applicability, offering a versatile, cost\u2010effective, and mechanism\u2010switchable sensing platform.\n                  <\/jats:p>","DOI":"10.1002\/asia.70829","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T03:25:57Z","timestamp":1781493957000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multifunctional Fluorescent Schiff Base Probe Derived From Chlorosalicylaldehyde for Selective Detection of Proteins, Nitroexplosives, Metal Ions and Antibiotics"],"prefix":"10.1002","volume":"21","author":[{"given":"Shunmugasundaram","family":"Gurusamy","sequence":"first","affiliation":[{"name":"Department of Chemistry V. O. Chidambaram College  Tuticorin Tamil Nadu India"},{"name":"Affiliated to Manonmaniam Sundranar University Abishekapatti  Tirunelveli Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devadasan Princess","family":"Jeba","sequence":"additional","affiliation":[{"name":"Department of Chemistry V. O. Chidambaram College  Tuticorin Tamil Nadu India"},{"name":"Affiliated to Manonmaniam Sundranar University Abishekapatti  Tirunelveli Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamilselvan","family":"Maharaja","sequence":"additional","affiliation":[{"name":"Department of Chemistry V. O. Chidambaram College  Tuticorin Tamil Nadu India"},{"name":"Affiliated to Manonmaniam Sundranar University Abishekapatti  Tirunelveli Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7406-9017","authenticated-orcid":false,"given":"Murugesan","family":"Sankarganesh","sequence":"additional","affiliation":[{"name":"Department of Chemistry Saveetha School of Engineering Saveetha Institute of Medical and, Technical Sciences  Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7097-4658","authenticated-orcid":false,"given":"Veerasamy","family":"Sathish","sequence":"additional","affiliation":[{"name":"Department of Chemistry Bannari Amman Institute of Technology  Sathyamangalam Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6437-7366","authenticated-orcid":false,"given":"Pounraj","family":"Thanasekaran","sequence":"additional","affiliation":[{"name":"Department of Chemistry Pondicherry University  Puducherry India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alagarsamy","family":"Mathavan","sequence":"additional","affiliation":[{"name":"Department of Chemistry V. O. Chidambaram College  Tuticorin Tamil Nadu India"},{"name":"Affiliated to Manonmaniam Sundranar University Abishekapatti  Tirunelveli Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,14]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202311002"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.2c01550"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3MA00097D"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.optmat.2025.117561"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jorganchem.2023.122825"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895\u2010022\u201003037\u20107"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3906\/kim\u20101905\u201060"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2021.106381"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2024.124677"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3RA02416D"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2025.127420"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2014.04.060"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2024.117558"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2022.114530"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2023.115105"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1MA00478F"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsaelm.5c00123"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11020191"},{"key":"e_1_2_8_20_1","first-page":"5","article-title":"A Systemic Review of Schiff Bases as an Analgesic, Anti\u2010Inflammatory","volume":"4","author":"Pandurangan K. R. A.","year":"2012","journal-title":"International Journa ofl Current Pharmaceutical Research"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijfs.12458"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895\u2010015\u20101604\u20103"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.09.013"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medidd.2025.100218"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201015890\u20104"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.4c01751"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rechem.2025.102404"},{"key":"e_1_2_8_28_1","first-page":"1","article-title":"Emerging Pharmaceutically Active Drugs: Synthesis and Pharmacology of Schiff Base Ligands With Their Metal Complexes","volume":"153","author":"Uddin E.","year":"2025","journal-title":"Discover Chemistry"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.110173"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemin.2025.100273"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2021.113558"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3906\/kim\u20101905\u201060"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2025.127420"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.optmat.2025.117561"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2024.124677"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12127\u2010013\u20100122\u20108"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2015.11.013"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2021.127303"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2CC06529K"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10904\u2010015\u20100234\u20101"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00240H"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.8b01717"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2022.113822"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2021.2009916"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21334"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.101925"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0308\u20108146(02)00155\u20103"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/b921606e"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2022.109716"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2021.113674"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2015.12.041"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dyepig.2020.108566"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.5012\/bkcs.2014.35.2.489"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2021.129785"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/la2034164"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202303559"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.microc.2025.116284"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1071\/CH11250"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10895\u2010015\u20101624\u2010z"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2015.12.041"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202303559"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1071\/CH11250"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2017.09.027"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotochem.2023.115214"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202204354"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.2c01439"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.201700660"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2023.123465"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126089"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201701852"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40985-018-0099-2"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.173346"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202302474"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.235"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.55730\/1300\u20100527.3381"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1080\/05704928.2023.2276925"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3SD00110E"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1MA01175H"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2020.129179"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.70175"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20235993"}],"container-title":["Chemistry \u2013 An Asian Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/asia.70829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/asia.70829","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/asia.70829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:08:51Z","timestamp":1784819331000},"score":1,"resource":{"primary":{"URL":"https:\/\/aces.onlinelibrary.wiley.com\/doi\/10.1002\/asia.70829"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":80,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/asia.70829"],"URL":"https:\/\/doi.org\/10.1002\/asia.70829","archive":["Portico"],"relation":{},"ISSN":["1861-4728","1861-471X"],"issn-type":[{"value":"1861-4728","type":"print"},{"value":"1861-471X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70829"}}