{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:06:46Z","timestamp":1790960806945,"version":"4.1.0"},"reference-count":51,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T00:00:00Z","timestamp":1658966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001274","name":"Clothworkers\u2019 Company","doi-asserted-by":"publisher","award":["R011217 Autism M10 2011\/12"],"award-info":[{"award-number":["R011217 Autism M10 2011\/12"]}],"id":[{"id":"10.13039\/501100001274","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["RP\u2010PG\u20101211\u201020016"],"award-info":[{"award-number":["RP\u2010PG\u20101211\u201020016"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["213608\/Z\/18\/Z"],"award-info":[{"award-number":["213608\/Z\/18\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Autism Research"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. This study examines longitudinal and contemporaneous associations of adaptive functioning in autistic youth across a wide ability range. Parent\u2010reported autism symptoms, co\u2010occurring emotional, behavioral and attention deficit hyperactivity disorder (ADHD) symptoms, and IQ were assessed in early childhood (\n                      <jats:italic>M<\/jats:italic>\n                      age 7\u2009years; T1) and 6\u2009years later in adolescence (\n                      <jats:italic>M<\/jats:italic>\n                      age 13\u2009years; T2) in 179 autistic youth. Adaptive functioning was assessed at T2. Structural equation modeling estimated pathways to adaptive functioning from autism, and psychiatric symptoms at T1 and T2, testing whether associations were driven by continuity of behaviors from T1 to T2 or their contemporaneous effect at T2, or both, controlling for T1 IQ. Lower adaptive functioning at T2 was associated with higher T1 and T2 ADHD symptoms (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.14, and\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.21) but not behavioral nor emotional symptoms at either timepoint. Lower adaptive functioning at T2 was also associated with lower T1 IQ (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a00.43) and higher social communication symptoms (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u00a0=\u00a0\u22120.37) at T2 but not T1, but the relationship with ADHD symptoms remained. Paths were not moderated by sex or IQ. Increased symptoms of ADHD, both in early childhood and contemporaneously, were associated with reduced adaptive functioning in adolescence. Co\u2010occurring ADHD may be a modifiable risk factor for adaptive function impairments and should be routinely assessed and when present evidence\u2010based treatments initiated which may benefit adaptive functioning outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Lay Summary<\/jats:title>\n                    <jats:p>Adaptive functioning is lower in many autistic individuals to a greater extent than would be expected based on IQ. However, the clinical features associated with these difficulties are less well understood. In a community sample higher attention deficit\/hyperactivity disorder (ADHD) symptoms, but not emotional or behavioral symptoms, in both early childhood and contemporaneously were associated with lower adaptive functioning in autistic adolescents. Co\u2010occurring ADHD may be a modifiable risk factor for adaptive function difficulties in autism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/aur.2785","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T06:45:26Z","timestamp":1658990726000},"page":"1883-1893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Pathways to adaptive functioning in autism from early childhood to adolescence"],"prefix":"10.1002","volume":"15","author":[{"given":"Susie","family":"Chandler","sequence":"first","affiliation":[{"name":"Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7455-5514","authenticated-orcid":false,"given":"Virginia","family":"Carter Leno","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology &amp; Neuroscience King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippa","family":"White","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology &amp; 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