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These motor symptoms often manifest in early childhood, making them critical targets for early diagnosis and intervention. This study aimed to assess whether kinematic features from a naturalistic grasping task could accurately distinguish autistic participants from non\u2010autistic ones. We analyzed grasping movements of autistic and non\u2010autistic young adults, tracking two markers placed on the thumb and index finger. Using a subject\u2010wise cross\u2010validated classifiers, we achieved accuracy scores of above 84%. Receiver operating characteristic analysis revealed strong classification performance with area under the curve values of above 0.95 at the subject\u2010wise analysis and above 0.85 at the trial\u2010wise analysis. These findings indicate strong reliability in accurately distinguishing autistic participants from non\u2010autistic ones. These findings suggest that subtle motor control differences can be effectively captured, offering a promising approach for developing accessible and reliable diagnostic tools for autism.<\/jats:p>","DOI":"10.1002\/aur.70049","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T11:00:09Z","timestamp":1746442809000},"page":"1170-1181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effective Autism Classification Through Grasping Kinematics"],"prefix":"10.1002","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3758-3855","authenticated-orcid":false,"given":"Erez","family":"Freud","sequence":"first","affiliation":[{"name":"Department of Psychology York University  Toronto Canada"},{"name":"Centre for Vision Research York University  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoha","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Centre for Vision Research York University  Toronto Canada"},{"name":"Department of Biology York University  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eitan","family":"Shelef","sequence":"additional","affiliation":[{"name":"Department of Geology and Environmental Science University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bat Sheva","family":"Hadad","sequence":"additional","affiliation":[{"name":"Department of Special Education and the Edmond J. 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