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However, the consistent findings thus far have been elusive. To examine whether individuals with ASD show rsFC differently than healthy individuals at multiple seed levels, we performed a systematic analysis and meta\u2010analysis at all prior seeds, functional network seeds, and single seed levels. This study was registered in the PROSPERO (registration number CRD42024559418). Publications were identified in PubMed, Embase, and PsycINFO from database inception until December 20, 2023. Publications were included that provided seed\u2010based whole\u2010brain rsFC contrasts between a sample with ASD and controls at rest. Seed and peak effect coordinates and intergroup effects were extracted for analysis. Random\u2010effects meta\u2010analysis was performed using the Seed\u2010based\n                    <jats:italic>d<\/jats:italic>\n                    Mapping software. This study included 26 studies from 709 people with ASD and 705 controls. The frontal regions, right medial cingulate gyrus (MCG) (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u22120.51; 95% CI, \u22120.69 to \u22120.33) of the ventral attention network (VAN), and medial left superior frontal gyrus (\n                    <jats:italic>g<\/jats:italic>\n                    \u2009=\u2009\u22120.42; 95% CI, \u22120.60 to \u22120.24) of the DMN were the most robust peak clusters at all prior seeds, functional network seeds, and medial prefrontal cortex seed level respectively. The findings not only support DMN dysfunction in people with ASD but also provide the first evidence of meta\u2010analysis to suggest VAN dysfunction in individuals with ASD.\n                  <\/jats:p>","DOI":"10.1002\/aur.70128","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T04:20:49Z","timestamp":1761020449000},"page":"2463-2477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Multilevel Resting\u2010State Dysfunctional Connectivity in People With Autism Spectrum Disorder: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"18","author":[{"given":"Xinyun","family":"Lin","sequence":"first","affiliation":[{"name":"School of Public Health (Shenzhen) Shenzhen Campus of Sun Yat\u2010Sen University  Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simin","family":"Deng","sequence":"additional","affiliation":[{"name":"School of Public Health (Shenzhen) Shenzhen Campus of Sun Yat\u2010Sen University  Guangdong China"},{"name":"Department of Rehabilitation Medicine Dongguan Eighth People's Hospital  Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8084-9706","authenticated-orcid":false,"given":"Xiuhong","family":"Li","sequence":"additional","affiliation":[{"name":"School of Public Health (Shenzhen) Shenzhen Campus of Sun Yat\u2010Sen University  Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhv191"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2018.10.077"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2013.00251"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1362361320969258"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2005.1634"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910340409"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2003.06.001"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00339.2011"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.01.010"},{"issue":"23","key":"e_1_2_16_12_1","first-page":"1","article-title":"The Effect of Learning to Drum on Behavior and Brain Function in Autistic Adolescents","volume":"119","author":"Cahart M. 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