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As the cartilage niche is composed of several stimulating factors, a multifunctional substrate providing topographical features while having the capability of electrical stimulation is presented. Herein, we demonstrate a biocompatible and conductive chondrocyte cell\u2010imprinted substrate using polydimethylsiloxane (PDMS) and carbon nanotubes (CNTs) as conductive fillers. Unlike the conventional silicon wafers or structural photoresist masters used for molding, cell surface topographical replication is challenging as biological cells showed extremely sensitive to chemical solvent residues during molding. The composite showed no significant difference compared with PDMS with regard to cytotoxicity, whereas an enhanced cell adhesion was observed on the conductive composite's surface. Integration of nanomaterials into the cell seeding scaffolds can make tissue regeneration process more efficient.<\/jats:p>","DOI":"10.1002\/bab.1741","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T16:43:24Z","timestamp":1551372204000},"page":"445-453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A conductive cell\u2010imprinted substrate based on CNT\u2013PDMS composite"],"prefix":"10.1002","volume":"66","author":[{"given":"Hanie","family":"Kavand","sequence":"first","affiliation":[{"name":"Department of Life Science Engineering Faculty of New Sciences and Technologies University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9311-2260","authenticated-orcid":false,"given":"Mahdi","family":"Rahaie","sequence":"additional","affiliation":[{"name":"Department of Life Science Engineering Faculty of New Sciences and Technologies University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javad","family":"Koohsorkhi","sequence":"additional","affiliation":[{"name":"Advanced Micro and Nano Devices Lab Faculty of New Sciences and Technologies University of Tehran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nooshin","family":"Haghighipour","sequence":"additional","affiliation":[{"name":"National Cell Bank of Iran Pasteur Institute of Iran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahin","family":"Bonakdar","sequence":"additional","affiliation":[{"name":"National Cell Bank of Iran Pasteur Institute of Iran  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstl.1742.0079"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23670"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/JSA.0000000000000182"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2013.0771"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/joca.1999.0306"},{"key":"e_1_2_7_7_1","unstructured":"Musumeci G.(2016)\/"},{"journal-title":"Artif. 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