{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:30:35Z","timestamp":1786977035647,"version":"build-2736575974"},"reference-count":37,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["iubmb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biotech and App Biochem"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Piper longum<\/jats:italic>\n                    L. (long pepper) is an economically and industrially important medicinal plant. However, the characterization of its volatiles has only been analyzed by gas chromatography\u2013mass spectrometry (GC\u2013MS). In the present study, precise characterization of\n                    <jats:italic>P. longum<\/jats:italic>\n                    fruit volatiles has been performed for the first time through advanced two\u2010dimensional gas chromatography\u2013time\u2010of\u2010flight spectrometry (GC\u00d7GC\u2013TOFMS). A total of 146 constituents accounting for 93.79% were identified, of which 30 were reported for the first time. All these constituents were classified into alcohols (4.5%), alkanes (8.9%), alkenes (6.71%), esters (6.15%), ketones (0.58%), monoterpene hydrocarbons (1.64%), oxygenated monoterpenes (2.24%), sesquiterpene hydrocarbons (49.61%), oxygenated sesquiterpenes (13.03%), phenylpropanoid (0.23%), and diterpenes (0.2%). Among all the classes, sesquiterpene hydrocarbons were abundant, with germacrene\u2010D (2.87% \u00b1 0.01%) as the major one, followed by 8\u2010heptadecene (2.69% \u00b1 0.03%),\n                    <jats:italic>\u03b2<\/jats:italic>\n                    \u2010caryophyllene (2.43% \u00b1 0.03%),\n                    <jats:italic>n<\/jats:italic>\n                    \u2010heptadecane (2.4% \u00b1 0.04%),\n                    <jats:italic>n<\/jats:italic>\n                    \u2010pentadecane (2.11% \u00b1 0.05%), and so forth. Further, 20 constituents were observed to be coeluted and separated precisely in the two\u2010dimensional column. The investigation provides an extensive metabolite profiling of\n                    <jats:italic>P. longum<\/jats:italic>\n                    fruit volatiles, which could be helpful to improve its therapeutic potential.\n                  <\/jats:p>","DOI":"10.1002\/bab.2567","type":"journal-article","created":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T01:44:50Z","timestamp":1709689490000},"page":"670-680","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Metabolite profiling of\n                    <i>Piper longum<\/i>\n                    L. fruit volatiles by two\u2010dimensional gas chromatography and time\u2010of\u2010flight mass spectrometry: Insights into the chemical complexity"],"prefix":"10.1002","volume":"71","author":[{"given":"Manaswini","family":"Dash","sequence":"first","affiliation":[{"name":"Centre for Biotechnology Siksha O Anusandhan (Deemed to be University)  Bhubaneswar 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