{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:59:56Z","timestamp":1775797196330,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate outcomes of patients diagnosed with oncocytic renal neoplasms on routine renal mass biopsy and to describe the natural history of these tumours when managed with surveillance as opposed to immediate intervention. To report disease\u2010specific survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Patients were identified from a retrospective review of pathology databases from three tertiary referral centres that utilise renal mass biopsy in routine clinical practice. All patients with biopsy\u2010proven oncocytic tumours were included and a retrospective review of online patient records was undertaken.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 184 biopsy\u2010proven oncocytic renal neoplasms identified in 172 patients. There were two biopsy complications (both pneumothorax, Clavien\u2013Dindo Grade I). Of these lesions, 135 were reported as oncocytomas or oncocytic renal neoplasms that were not further classified and 37 were reported as chromophobe carcinoma (ChRCC). The median age at diagnosis was 70 (33\u201388). The average tumour diameter at diagnosis was 33\u2009mm. One hundred seven tumours were initially managed with surveillance (including 13 ChRCC) with a minimum follow\u2010up of 6\u2009months and a median of 39\u2009months (6\u2013144) whereas 49 patients underwent immediate treatment. The mean growth rate across all oncocytic renal neoplasms managed by surveillance was 3\u2009mm\/year. There was no statistically significant difference in growth rates between oncocytic renal neoplasms and ChRCC. Thirteen patients with oncocytic renal neoplasms initially managed by surveillance moved on to an active management strategy during follow\u2010up. The clinical indication given for a change from surveillance was tumour growth in 12 cases and patient choice in 1 case. Where definitive pathology was available, there was 85% concordance with the biopsy. There were no cases of development of metastatic disease or disease\u2010related morbidity or mortality during the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This multicentre retrospective cohort study supports the hypothesis that selected biopsy\u2010proven oncocytic renal neoplasms can be safely managed with surveillance in the medium term. Routine renal mass biopsy may reduce surgery for benign or indolent renal tumours and the potential associated morbidity for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bco2.141","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T04:52:26Z","timestamp":1646283146000},"page":"291-297","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Real world outcomes of biopsy\u2010proven oncocytic neoplasm of the kidney managed by surveillance"],"prefix":"10.1002","volume":"3","author":[{"given":"Flora E.","family":"Rodger","sequence":"first","affiliation":[{"name":"Department of Urology Queen Elizabeth University Hospital  Glasgow UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiran","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Urology Western General Hospital  Edinburgh 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