{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T05:02:35Z","timestamp":1781499755304,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T00:00:00Z","timestamp":1673308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study is to evaluate the 2015 introduction of prebiopsy magnetic resonance imaging of the prostate (MRI\u2010P) as the standard of care for diagnosing prostate cancer (PCa) by the Norwegian public health care authorities. There were three specific objectives of this study: first, to evaluate the consequences of using different TNM manuals for clinical T\u2010staging (cT\u2010staging) in a national setting; second, to determine if the data reveals that MRI\u2010P based cT\u2010staging is superior to digital rectal examination (DRE)\u2010based cT\u2010staging compared with pathological T\u2010stage (pT\u2010stage) post radical prostatectomy; and third, to assess whether treatment allocations have changed over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>All patients registered in the Norwegian Prostate Cancer Registry between 2004 and 2021 were retrieved and 5538 were eligible for inclusion. Concordance between clinical T\u2010stage (cT\u2010stage) and pT\u2010stage was assessed by percentage agreement, Cohen's kappa and Gwet's agreement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>MR visualisation of lesions influences reporting of tumour extension beyond DRE findings. Agreement between cT\u2010stage and pT\u2010stage declined from 2004 to 2009, which coincided with an increase in the percentage being pT3. From 2010, agreement increased, which aligned with changes in cT\u2010staging and the introduction of MRI\u2010P. From 2017, regarding the reporting of cT\u2010DRE and cT\u2010Total (overall cT\u2010stage), agreement diminished for cT\u2010DRE but remained relatively stable (&gt;60%) for cT\u2010Total. Regarding treatment allocation, the study suggests that staging with MRI\u2010P has shifted treatment towards radiotherapy in locally advanced high\u2010risk disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Introduction of MRI\u2010P has affected cT\u2010stage reporting. Agreement between cT\u2010stage and pT\u2010stage appears to have improved. This study suggests that use of MRI\u2010P influences treatment decisions in certain patient subgroups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bco2.214","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T19:00:27Z","timestamp":1673377227000},"page":"331-338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Impact of prebiopsy MRI on prostate cancer staging: Results from the Norwegian Prostate Cancer Registry"],"prefix":"10.1002","volume":"4","author":[{"given":"Erik Skaaheim","family":"Haug","sequence":"first","affiliation":[{"name":"Department of Urology Vestfold Hospital Trust  T\u00f8nsberg Norway"},{"name":"Institute of Cancer Genomics and Informatics Oslo University Hospital  Oslo Norway"},{"name":"Cancer Registry of Norway  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor \u00c5ge","family":"Myklebust","sequence":"additional","affiliation":[{"name":"Cancer Registry of Norway  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4253-1283","authenticated-orcid":false,"given":"Patrick","family":"Julieb\u00f8\u2010Jones","sequence":"additional","affiliation":[{"name":"Department of Urology Haukeland University Hospital  Bergen Norway"},{"name":"Department of Clinical Medicine (K1) University of Bergen  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Anders Rokne","family":"Reis\u00e6ter","sequence":"additional","affiliation":[{"name":"Helse Bergen HF, Department of Radiology Haukeland University Hospital  Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsti","family":"Aas","sequence":"additional","affiliation":[{"name":"Department of Urology Oslo University Hospital  Oslo 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