{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T17:23:34Z","timestamp":1782926614371,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:00:00Z","timestamp":1699833600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report on the cost\u2010effectiveness of adjustable anchored single\u2010incision mini\u2010slings (mini\u2010slings) compared with tension\u2010free standard mid\u2010urethral slings (standard slings) in the surgical management of female stress urinary incontinence (SUI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>Data on resource use and quality were collected from women aged \u226518 years with predominant SUI undergoing mid\u2010urethral sling procedures in 21 UK hospitals. Resource use and quality of life (QoL) data were prospectively collected alongside the Single\u2010Incision Mini\u2010Slings versus standard synthetic mid\u2010urethral slings Randomised Control Trial (SIMS RCT), for surgical treatment of SUI in women. A health service provider's (National Health Service [NHS]) perspective with 3\u2010year follow\u2010up was adopted to estimate the costs of the intervention and all subsequent resource use. A generic instrument, EuroQol EQ\u20105D\u20103L, was used to estimate the QoL. Results are reported as incremental costs, quality adjusted life years (QALYs) and incremental cost per QALY.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Base case analysis results show that although mini\u2010slings cost less, there was no significant difference in costs: mini\u2010slings versus standard slings: \u00a3\u20106 [95% CI \u2212228\u2013208] or in QALYs: 0.005 [95% CI \u22120.068\u20130.073] over the 3\u2010year follow\u2010up. There is substantial uncertainty, with a 56% and 44% probability that mini\u2010slings and standard slings are the most cost\u2010effective treatment, respectively, at a \u00a320\u2009000 willingness\u2010to\u2010pay threshold value for a QALY.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>At 3\u2009years, there is no significant difference between mini\u2010slings and standard slings in costs and QALYs. There is still some uncertainty over the long\u2010term complications and failure rates of the devices used in the treatment of SUI; therefore, it is important to establish the long\u2010term clinical and cost\u2010effectiveness of these procedures.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bco2.303","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:04:28Z","timestamp":1699848268000},"page":"230-239","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Three\u2010year cost utility analysis of mini versus standard slings: A trial based economic evaluation"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3450-4536","authenticated-orcid":false,"given":"Mary","family":"Kilonzo","sequence":"first","affiliation":[{"name":"Health Economics Research Unit University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9786-8118","authenticated-orcid":false,"given":"Dwayne","family":"Boyers","sequence":"additional","affiliation":[{"name":"Health Economics Research Unit University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cooper","sequence":"additional","affiliation":[{"name":"Health Services Research Unit University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Davidson","sequence":"additional","affiliation":[{"name":"Health Services Research Unit University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3559-0034","authenticated-orcid":false,"given":"Kiron","family":"Bhal","sequence":"additional","affiliation":[{"name":"Department of Urogynaecology University Hospital of Wales  Cardiff Wales UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"N'Dow","sequence":"additional","affiliation":[{"name":"Academic Urology Unit University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme","family":"MacLennan","sequence":"additional","affiliation":[{"name":"The Centre for Healthcare Randomised Trials University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Norrie","sequence":"additional","affiliation":[{"name":"Usher Institute Edinburgh Clinical Trials Unit University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Abdel\u2010Fattah","sequence":"additional","affiliation":[{"name":"Institute of Applied Health Sciences University of Aberdeen  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01747.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1994.tb01749.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.01.007"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00598-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2005.09.004"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2111815"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-01511"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002087"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1997.tb11006.x"},{"key":"e_1_2_8_11_1","unstructured":"National Institute for Health and Care Excellence.Guide to the methods of technology appraisal [PMG9]. 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