{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:44:55Z","timestamp":1777628695544,"version":"3.51.4"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:00:00Z","timestamp":1776297600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate long\u2010term safety, urological complication rates and quality of life (QoL) associated with urethral intermittent catheterization (IC) over a 5\u2010year follow\u2010up in adult, established, experienced subjects with longstanding IC use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Prospective, noninterventional, observational cohort study at three European sites. Adults (\u226518\u2009years) performing urethral IC with LoFric\u2122 catheters for \u22656\u00a0years prior to enrolment were followed for 5\u00a0years. Outcomes included symptomatic urinary tract infections (UTIs), urethral strictures, bladder stones, prostatitis, epididymitis, patient\u2010reported outcomes (PROs) and perception of catheters and IC. QoL, including pain and discomfort, anxiousness and depression, self\u2010care and performing usual activities, was evaluated through the EQ 5DL questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety\u2010eight participants were enrolled (April 2015\u2013August 2018); 49 completed 5\u2010year follow\u2010up (PP). Median age at inclusion was 61\u2009years; 69% were male. Median follow\u2010up was 5\u00a0years; mean prior LoFric use was 13\u2009years (range 6\u201330). Neurological conditions comprised 51% of underlying aetiologies. Across 5\u00a0years, there were no significant changes in UTI frequency, other urological complications, EQ\u20105D tariff, or PRO ratings. At baseline, 59% (PP) reported \u22651 UTI in the prior 12\u2009months versus 55% at Year 5 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.8036); mean UTIs decreased from 3.93 to 3.63 (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u20090.5434). Urethral stricture reports rose from 6% to 12% (NS). EQ\u20105D tariff remained stable (mean 0.86 at inclusion and Year 5).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In adults with more than a decade of prior IC experience, continued use of hydrophilic LoFric catheters over an additional 5\u00a0years was associated with unchanged complication rates and stable QoL and PROs, supporting the long\u2010term safety of IC as a bladder management strategy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70200","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T09:01:48Z","timestamp":1776330108000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long\u2010term intermittent catheterization: Safety and outcomes from a prospective observational study"],"prefix":"10.1002","volume":"7","author":[{"given":"Peter","family":"Taffo","sequence":"first","affiliation":[{"name":"Wellspect HealthCare  M\u00f6lndal Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"Amarenco","sequence":"additional","affiliation":[{"name":"Service de Neuro\u2010Urologie et Explorations P\u00e9rin\u00e9ales H\u00f4pital Piti\u00e9\u2010Salp\u00eatri\u00e8re  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Andersson","sequence":"additional","affiliation":[{"name":"Norrlands Universitetssjukhus Neurorehab, Neurocentrum  Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Morris","sequence":"additional","affiliation":[{"name":"Bristol Urological Institute (BUI), Southmead Hospital  Bristol UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"H\u00f6rling","sequence":"additional","affiliation":[{"name":"Wellspect HealthCare  M\u00f6lndal Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)61055-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.sc.3101348"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20929"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.337"},{"key":"e_1_2_10_6_1","unstructured":"VahrS Cobussen\u2010BoekhorstH EikenboomJ et al.Evidence\u2010based guideline for best practice in urological health care. 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