{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:13:45Z","timestamp":1790007225572,"version":"4.0.1"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study is to review initial urodynamics (UDS) findings in patients with multiple sclerosis (MS) related lower urinary tract symptoms, establish where UDS happen in treatment pathways and to evaluate the benefit of video over standard UDS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>OnaBotulinumToxin A (BTX\u2010A) na\u00efve, MS patients who had undergone UDS were identified from prospectively maintained databases from UK hospitals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred fifty\u2010seven patients were identified from seven UK departments. One (0.9%) female patient and 3 (6.7%) males had end fill pressures\u2009&gt;\u200940 cmH\n                      <jats:sub>2<\/jats:sub>\n                      O. No female and two (5.1%) males showed vesico\u2010ureteric reflux. Of female patients reporting pure overactive bladder (OAB) symptoms, 61 (67.2%) showed neurogenic detrusor overactivity (NDO), 10 (11.1%) showed loss of compliance (LoC) and 28 (31.1%) showed no NDO or LoC. Following UDS, 134 (85.4%) patients underwent management changes: 61 (72.6%) females and 25 (78.1%) males were offered non\u2010medical treatment, oral or topical medication; 30 (30.9%) females and 7 (18.9%) males were advised to start self\u2010catheterisation; 16 (19.0%) females and 4 (12.5%) males were offered intra\u2010vesical BTX\u2010A; two (2.4%) females were offered SUI surgery and one (3.1%) male was offered bladder outflow obstruction surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Many patients underwent UDS prior to conservative and medical management, which is earlier than most guidelines recommend, potentially delaying non\u2010invasive treatment. This study supports the need for VUDS at initial assessment of men with MS. Standard UDS suffice in women with MS and pure OAB symptoms unresponsive to conservative measures and oral medication unless they have abnormal renal function, hydronephrosis or significant post void volumes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70208","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:52:51Z","timestamp":1777431171000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Urodynamics assessment in patients with multiple sclerosis"],"prefix":"10.1002","volume":"7","author":[{"given":"Nicholas Faure","family":"Walker","sequence":"first","affiliation":[{"name":"Epsom and St Helier University Hospitals NHS Trust  Epsom UK"},{"name":"King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Bacon","sequence":"additional","affiliation":[{"name":"Bristol Urological Institute  Bristol 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