{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T09:01:31Z","timestamp":1785315691791,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This work aimed to investigate the role of surgeon experience on operating time and detection rate of clinically significant prostate cancer (csPCa) in a large contemporary cohort undergoing transperineal (TP) MRI\u2010targeted prostate biopsy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>We retrospectively reviewed patients who underwent TP MRI\u2010guided prostate biopsies between 10\/2018 and 04\/2024. Patients with suspicious MRI lesions (PI\u2010RADS 3, 4 and 5) formed the study cohort. All patients underwent MRI\u2010targeted biopsies of suspicious lesions combined with a standard 12\u2010core systematic biopsy. Caseloads\u2014both total and in increments of 50 cases\u2014were calculated for each surgeon. We employed univariable and multivariable Poisson regression models to analyse biopsy duration, and logistic regression models to assess csPCa detection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Out of 3336 MRI\u2010guided TP biopsies, 1148 (34%) involved PI\u2010RADS 3, 1398 (42%) PI\u2010RADS4 and 790 (24%) PI\u2010RADS 5 as index lesions. Most patients (55%) had one suspicious lesion. The median caseload per surgeon was 63 (IQR [interquartile range]: 30\u2013110). Biopsy duration significantly decreased after the first 50 procedures (13\u2009min [95% CI: 10\u201318] to 10\u00a0min [95% CI: 8\u201315]) and plateaued thereafter. Multivariable Poisson regression demonstrated increased caseload independently associated with shorter biopsy duration (IRR 0.891 [95% CI: 0.833\u20130.899],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The overall csPCa detection rate was 43%, with no significant correlation to caseload. These findings were consistent across subgroup analyses based on PI\u2010RADS score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This large, contemporary study demonstrated that biopsy duration decreased significantly after approximately 50 cases, indicating a learning curve without compromising the detection rate of csPCa.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70237","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T09:51:55Z","timestamp":1783504315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Procedure efficiency and diagnostic outcomes during the learning curve of transperineal MRI\u2010guided prostate biopsy"],"prefix":"10.1002","volume":"7","author":[{"given":"Mario","family":"Hallaschek","sequence":"first","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Kwe","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich","family":"Helke","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Platzek","sequence":"additional","affiliation":[{"name":"Department of Radiology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"B\u00f6hm","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Baunacke","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelika","family":"Borkowetz","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"},{"name":"Department of Urology University Medical Centre Rostock, University Medicine Rostock  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Herout","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benedikt","family":"Hoeh","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Carl Gustav Carus, TUD Dresden University of Technology  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"https:\/\/www.krebsdaten.de\/Krebs\/DE\/Content\/Krebsarten\/Prostatakrebs\/prostatakrebs_node.html2025[cited 2025 Nov 30]. 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