{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T09:01:31Z","timestamp":1785315691355,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82541021"],"award-info":[{"award-number":["82541021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L248017"],"award-info":[{"award-number":["L248017"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objective of this study is to assess contralateral renal parenchymal volume (CRPV) changes in patients with renal cell carcinoma (RCC) after PN and identify the clinical factors associated with CRPV increase.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study included 143 RCC patients (aged 24\u201376\u2009years) who underwent PN between 2017 and 2018. Preoperative and postoperative CRPV were assessed using 3D Slicer software. Patients were categorized into CRPV\u2010increase and CRPV\u2010decrease groups based on volumetric changes. Univariate and multivariable logistic regression analyses were conducted to determine independent factors influencing CRPV increase.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      With a median follow\u2010up of 904\u2009days (IQR: 605\n                      <jats:bold>\u2013<\/jats:bold>\n                      1707), the overall median CRPV increase was 4.1% (IQR: \u22122.8% to 12.6%) relative to the preoperative volume, and 68.5% (98\/143) of patients exhibited CRPV enlargement. Multivariable analysis identified postoperative acute kidney injury (AKI) as a significant independent predictor associated with CRPV increase (OR\u2009=\u20092.990, 95% CI: 1.050\u20138.513,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040), whereas preexisting hypertension was inversely associated with CRPV growth (OR\u2009=\u20090.446, 95% CI: 0.206\u20130.966,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.041).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Contralateral renal compensation following PN is relatively modest compared to radical nephrectomy. Postoperative AKI is associated with compensatory renal hypertrophy, whereas hypertension is negatively associated with this process. These hypothesis\u2010generating findings underscore the importance of perioperative renal function management and blood pressure control. Prospective studies are needed to validate these associations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70249","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T06:48:07Z","timestamp":1784789287000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with contralateral renal parenchymal volume changes after partial nephrectomy: A retrospective cohort study"],"prefix":"10.1002","volume":"7","author":[{"given":"Qilong","family":"Jiao","sequence":"first","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4233-8005","authenticated-orcid":false,"given":"Jialong","family":"Song","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Cao","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwen","family":"Chen","sequence":"additional","affiliation":[{"name":"Senior Department of Nephrology, Chinese PLA General Hospital, Nephrology Institute of the Chinese PLA, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases Beijing Key Laboratory of Kidney Disease Research  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaopeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology, First Medical Center Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibo","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Peng","sequence":"additional","affiliation":[{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology, First Medical Center Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingbo","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4283-409X","authenticated-orcid":false,"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Medicine Nankai University  Tianjin China"},{"name":"Senior Department of Urology Chinese PLA General Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.03.006"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2016.08.060"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.57.030195.001403"},{"issue":"1","key":"e_1_2_10_5_1","first-page":"1","article-title":"Compensatory renal enlargement. 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