{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T09:01:31Z","timestamp":1785315691403,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:00:00Z","timestamp":1784073600000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objective of this study is to evaluate the incidence, timing, anatomical characteristics, predictors and management outcomes of urethral stricture formation following HoLEP at an academic institution in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A retrospective review was conducted of 857 patients who underwent HoLEP at a single academic institution between July 2017 and August 2025. Patients with prior or incidental urethral stricture diagnosis at the time of HoLEP were excluded. Enucleation was performed using a 26\u2010Fr resectoscope, and morcellation was completed through a 26\u2010Fr morcelloscope sheath. If initial cystoscopy suggested small\u2010sized meatus or non\u2010distensible penile urethra, Otis urethrotomy or urethral calibration was performed. Demographic, clinical and perioperative data were collected and analysed using multivariable logistic regression to identify predictors of postoperative urethral stricture formation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 857 patients, 16 had preoperative or intraoperative strictures and were excluded. Seventeen patients (2.0%) developed urethral stricture at a mean of 6.2\u00a0months postoperatively. Patients with stricture had lower BMI (24.1 vs. 27.4\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0042) and smaller prostates (65 vs. 105\u2009ml,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u200970.0131). Median age was higher in the stricture group (73 vs. 69\u2009years,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0702). On multivariable analysis, higher BMI was independently associated with lower odds of postoperative urethral stricture. (OR 0.84, 95% CI 0.73\u20130.97;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016). Stricture locations included bulbar (52.9%), bulbo\u2010membranous (11.8%), sub\u2010meatal (11.8%), penile (5.9%), membranous (5.9%), prostatic (5.9%) and combined bulbar and sub\u2010meatal (5.9%). Most strictures (76.5%) were &lt;1\u00a0cm. Initial management included laser incision (seven), dilation (nine) and drug\u2010coated balloon dilation (one). At mean post\u2010treatment follow\u2010up of 17.53\u2009months, four patients (23.5%) experienced recurrence of stricture that required additional management.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The overall risk of urethral stricture following HoLEP was low (2%). Higher BMI was associated with a lower risk of urethral stricture formation. Following initial intervention, 23.5% experienced relapse needing additional management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70251","type":"journal-article","created":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T10:04:26Z","timestamp":1784109866000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["New\u2010Onset Urethral Stricture After HoLEP: Incidence, Predictors and Treatment Outcomes From an 8\u2010Year Single\u2010Centre Analysis"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1468-6085","authenticated-orcid":false,"given":"Juanita","family":"Velasquez\u2010Ospina","sequence":"first","affiliation":[{"name":"Desai Sethi Urology Institute, Miller School of Medicine University of Miami  Miami Florida 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