{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T04:19:44Z","timestamp":1787717984387,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This work aimed to determine the pathological yield of restaging transurethral resection of bladder tumour (re\u2010TURBT) in patients with non\u2010muscle\u2010invasive bladder cancer (NMIBC) managed at a contemporary tertiary\u2010care setting and to describe clinicopathological features among patients with positive restaging histopathology to select patients most likely to benefit from re\u2010TURBT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This single\u2010centre retrospective observational case\u2013control analysis within a re\u2010TURBT cohort included patients who underwent macroscopically complete index TURBT for presumed NMIBC and subsequently underwent restaging TURBT within the institutional pathway. Patients with muscle\u2010invasive disease at index TURBT, benign pathology, non\u2010urothelial carcinoma, variant histology, or ineligibility for re\u2010TURBT for any reason were excluded. The primary outcome was positive restaging histopathology, defined as residual urothelial neoplasia or pathological progression. In addition, clinicopathological variables were explored to identify factors potentially associated with positive re\u2010TURBT, including tumour size, multifocality, age, sex, tumour grade, detrusor muscle status, and carcinoma in situ on index histopathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 188 TURBT records assessed, 79 patients underwent re\u2010TURBT and formed the analysed cohort. Median age was 64\u2009years (IQR 56\u201369), 69 patients (87.3%) were male, and detrusor muscle was present in 77 index specimens (97.5%). Positive restaging histopathology occurred in nine patients (11.4%), comprising residual disease in eight (10.1%) and Ta high\u2010grade to T1 high\u2010grade progression in one (1.3%); no muscle\u2010invasive upstaging was observed. In the T1\u2010only analysis, positivity occurred in 8\/69 (11.6%). Larger tumours, multifocality and CIS were more frequent among positive cases. Follow\u2010up recurrence admission occurred in 9 patients (11.4%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this contemporary re\u2010TURBT series, the pathological yield of restaging was low, with uncommon progression. Positivity clustered in those with larger tumours (\u22653\u00a0cm) and high\u2010risk biology (multifocal disease and carcinoma in situ on index histopathology). These findings are hypothesis\u2010generating and support prospective evaluation of selective restaging strategies in the contemporary era.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70269","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T05:50:28Z","timestamp":1787291428000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reassessing re\u2010TURBT in the modern era: Is it time to move from routine to selective?"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7946-5401","authenticated-orcid":false,"given":"Mithilesh","family":"Yadav","sequence":"first","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5747-3966","authenticated-orcid":false,"given":"Swarnendu","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2065-1447","authenticated-orcid":false,"given":"Sambit","family":"Tripathy","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1082-9421","authenticated-orcid":false,"given":"Pranjal","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8712-5655","authenticated-orcid":false,"given":"Vivek","family":"Rathod","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-3131","authenticated-orcid":false,"given":"Manoj Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7959-6465","authenticated-orcid":false,"given":"Kalandi","family":"Barik","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4913-0941","authenticated-orcid":false,"given":"Prasant","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Urology and Renal Transplant All India Institute of Medical Sciences (AIIMS)  Bhubaneswar India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"EAU Guidelines","author":"European Association of Urology","year":"2025"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000003846"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0041"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000070437.14275.e0"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2018.02.014"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.07.005"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.1514"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2023.07.002"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2009.05.047"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12894-023-01278-7"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01522-9"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000075961"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.031"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.07.016"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2022.106777"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2021.06.011"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.03.007"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-199907000-00018"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.4111\/icu.20210314"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0302-2838(02)00068-4"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.70082"}],"container-title":["BJUI Compass"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bco2.70269","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T03:42:10Z","timestamp":1787715730000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1002\/bco2.70269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/bco2.70269"],"URL":"https:\/\/doi.org\/10.1002\/bco2.70269","archive":["Portico"],"relation":{},"ISSN":["2688-4526","2688-4526"],"issn-type":[{"value":"2688-4526","type":"print"},{"value":"2688-4526","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2026-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70269"}}