{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:11:36Z","timestamp":1790604696222,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study is to descriptively evaluate the reported functional and symptomatic outcomes of Aquablation therapy across published series categorized by operator experience level.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects\/Patients and Methods<\/jats:title>\n                    <jats:p>\n                      We performed a non\u2010systematic descriptive review of functional and symptomatic outcomes of eight published Aquablation clinical trials and real\u2010world series. Studies were categorized based on inferred or known operator experience into early\u2010experience (Water, Water II and Japan\u2010PMS; total\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009332) and experienced groups (Water III, ASC Pilot, ASC Global, Mount Sinai and Madrid; total\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009664). Extracted variables included baseline and follow\u2010up International Prostate Symptom Score (IPSS), IPSS\u2010quality of life (QoL), maximum urinary flow rate (Qmax) and post\u2010void residual volume (PVR). Weighted and sample\u2010size weighted mean and standard deviation of change were calculated and evaluated descriptively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>IPSS, IPSS\u2010QoL, Qmax and PVR all improved across the eight cohorts. Mean changes in patient\u2010reported outcomes were similar between early\u2010experience and experienced cohorts for IPSS (unweighted mean change: \u221214.77 vs. \u221215.15; weighted: \u221214.81 vs. \u221215.30) and IPSS\u2010QoL (unweighted: \u22123.13 vs.\u2009\u22123.28; weighted: \u22123.14 vs. \u22123.13). Physiologic metrics (QMax and PVR) demonstrated higher absolute improvements and greater variance in the experienced cohort, heavily driven by cohorts with more severe baseline urinary retention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Across published series, Aquablation yields broadly consistent improvements in patient\u2010reported symptom scores, regardless of baseline operator experience level. Observed differences in physiological outcomes appear primarily influenced by baseline patient selection rather than surgeon experience. These descriptive findings support the general reproducibility of Aquablation outcomes across real\u2010world clinical settings. Formal prospective studies are required to define reproducibility across perioperative safety profiles.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70282","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:43:57Z","timestamp":1789955037000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reproducibility of Aquablation outcomes across surgeon experience levels: A descriptive analysis of published studies"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2469-4644","authenticated-orcid":false,"given":"Eviatar","family":"Fields","sequence":"first","affiliation":[{"name":"Faculty of Medicine McGill University  Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2867-9723","authenticated-orcid":false,"given":"Mario Henrique Bitar","family":"Siqueira","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgery University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7775-2812","authenticated-orcid":false,"given":"Philip","family":"Charlesworth","sequence":"additional","affiliation":[{"name":"The Royal Marsden Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3120-0256","authenticated-orcid":false,"given":"Garrett","family":"Pohlman","sequence":"additional","affiliation":[{"name":"Kearney Urology Center PC  Kearney Nebraska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Cuellar","sequence":"additional","affiliation":[{"name":"Urology Austin PLLC  Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1428-9736","authenticated-orcid":false,"given":"Shin","family":"Koike","sequence":"additional","affiliation":[{"name":"Itabashi Chuo Medical Center  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2679-2635","authenticated-orcid":false,"given":"Naeem","family":"Bhojani","sequence":"additional","affiliation":[{"name":"Division of Urology Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al (CHUM)  Montr\u00e9al Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilal","family":"Chughtai","sequence":"additional","affiliation":[{"name":"Plainview Hospital, Smith Institute of Urology Northwell Health  Syosset New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin C.","family":"Zorn","sequence":"additional","affiliation":[{"name":"Prostate Surgical Institute BPH Canada  Montreal 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