{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:36:14Z","timestamp":1793093774994,"version":"4.5.0"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to quantify discrepancies in non\u2013high\u2010risk non\u2013muscle\u2010invasive bladder cancer (NMIBC) stratification between the National Institute for Health and Care Excellence (NICE) and the European Association of Urology (EAU) guidelines, compare discriminative performance for predicting recurrence, estimate potentially missed recurrences under shorter surveillance and calculate per\u2010patient surveillance costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>This is a retrospective cohort study of patients undergoing transurethral resection of bladder tumour (TURBT) at a UK tertiary centre (2018\u20132020). Patients with low\u2010 or intermediate\u2010risk NMIBC who completed 5\u2010year follow\u2010up or experienced recurrence were included. Each patient was stratified according to both NICE and EAU (WHO 1973) guidelines. Outcomes included recurrence rate, discriminative accuracy (Harrell's C\u2010index), proportion of recurrences occurring beyond NICE discharge timepoints and surveillance cost based on NHS reference prices.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 158 eligible patients (78% male; mean age 68\u2009years), 40% were assigned different risk categories depending on guideline applied. NICE classified significantly more patients as low risk than EAU (31.1% vs. 12.7%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Overall, 5\u2010year recurrence was 48.7%, with no significant difference in recurrence rates between corresponding risk groups under each guideline. NICE demonstrated superior discrimination (C\u2010index 0.605 vs. 0.511;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006). Among NICE low\u2010risk patients, 45% of recurrences occurred between Years 2 and 5\u2014beyond the recommended 1\u2010year discharge point. Mean per\u2010patient surveillance cost was \u00a31412 under NICE versus \u00a33525 under EAU, representing a 60% reduction.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>NICE can reduce cost with comparable discrimination efficiency to EAU guidelines, but risks missed recurrences; a hybrid NICE\u2013EAU approach may offer the optimal balance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70283","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:06:26Z","timestamp":1792033586000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["NEITHER study: NICE versus EAU inconsistent triage, expenses and reliability in non\u2013high\u2010risk non\u2010muscle invasive bladder cancer surveillance"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0931-9707","authenticated-orcid":false,"given":"Youssef","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1828-2117","authenticated-orcid":false,"given":"Luis","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"St George's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Heelan","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1153-5249","authenticated-orcid":false,"given":"Martina","family":"Spazzapam","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"},{"name":"Centre for Transplantation, Urology and Kidney Disease King's College  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Findlay","family":"Macaskill","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyara","family":"Fernando","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1745-3025","authenticated-orcid":false,"given":"Adham","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Addenbrooke's Hospital  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Hussien","sequence":"additional","affiliation":[{"name":"St George's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0969-5067","authenticated-orcid":false,"given":"Mohammed","family":"Gad","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumitra","family":"Chakravarti","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Mokbel","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Nair","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh","family":"Thurairaja","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Shamim","family":"Khan","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmin","family":"Abughanem","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsie","family":"Mensah","sequence":"additional","affiliation":[{"name":"Guy's Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.3816"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2005.12.031"},{"key":"e_1_2_15_4_1","first-page":"635","article-title":"EAU risk tables for NMIBC: update","volume":"79","author":"Sylvester RJ","year":"2021","journal-title":"Eur Urol"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2021.08.010"},{"key":"e_1_2_15_6_1","volume-title":"Bladder cancer: diagnosis and management. 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