{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T06:42:30Z","timestamp":1792392150278,"version":"4.4.0"},"reference-count":38,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:00:00Z","timestamp":1792281600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of this study is to investigate long\u2010term fertility outcomes following orchidopexy performed for testicular torsion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>This systematic review adhered to the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses (PRISMA) guidelines and was registered with the International Prospective Register of Systematic Reviews (PROSPERO: CRD420251152057). A literature search was conducted from June 2025 to October 2025 across Scopus, PubMed, Web of Science and the StarPlus Library (University of Sheffield). Studies reporting on male patients with a history of testicular torsion who underwent orchidopexy were included. Eligible study designs comprised case reports\/series, cohort studies, case\u2013control studies and randomised controlled trials. Studies involving cryptorchidism, orchidectomy or no intervention following exploration, as well as systematic reviews, meta\u2010analyses, editorials, book chapters, conference proceedings\/posters, reviews and commentaries, were excluded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seventeen articles with 324 patients analysed fertility and hormonal outcomes following detorsion with orchidopexy. Primary outcomes were classified as fertility parameters and semen analysis. Reported pregnancy rates were high, ranging from 90.2% to 91.3% with reported time to pregnancy of 6.6 to 8.9\u2009months. Six studies reported semen parameters with sperm count (11.2\u2013235.4\u2009\u00d7\u200910), motility (51.6\u201367%) and morphology (3.6\u201328%) generally within reported reference ranges, although substantial variability existed between studies. Secondary outcomes included hormonal analysis and anti\u2010sperm antibody prevalence. Five studies reported hormonal follicle\u2010stimulating hormone (FSH) and luteinising hormone (LH) levels, eight studies reported testosterone levels and two reported inhibin B levels. Anti\u2010sperm antibodies (ASA) were described in two studies, with positive ASA ranging from 20% to 27.2%. The reported follow\u2010up duration across nine studies was 0.12\u201311.8\u2009years, although none reported fertility outcomes longitudinally.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This review suggests that fertility potential is generally preserved following testicular detorsion with orchidopexy, with the majority of studies reporting favourable semen profiles and pregnancy outcomes. However, the small number of heterogeneous studies and limited long\u2010term data highlight the need for larger, standardised studies to better define the long\u2010term impact of testicular torsion on fertility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70287","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:56:55Z","timestamp":1792389415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does orchidopexy for testicular torsion affect long\u2010term fertility parameters in males: A systematic review"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5241-9079","authenticated-orcid":false,"given":"Avula Aishwarya","family":"Rao","sequence":"first","affiliation":[{"name":"Sheffield Medical School University of Sheffield  Sheffield UK"},{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Shariq","family":"Rahemtoola","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"},{"name":"Department of Urology Manchester Royal Infirmary  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4596-4745","authenticated-orcid":false,"given":"Hassaan","family":"Aziz","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7366-4233","authenticated-orcid":false,"given":"Peter","family":"Grice","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"},{"name":"Department of Urology Manchester Royal Infirmary  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1611-999X","authenticated-orcid":false,"given":"Mohamed","family":"Mubarak","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7710-0531","authenticated-orcid":false,"given":"Ian","family":"Pearce","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"},{"name":"Department of Urology Manchester Royal Infirmary  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodora","family":"Stasinou","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"},{"name":"Department of Urology Manchester Royal Infirmary  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1517-6184","authenticated-orcid":false,"given":"Vaibhav","family":"Modgil","sequence":"additional","affiliation":[{"name":"Manchester Andrology Research Collaborative (MARC) Manchester University NHS Foundation Trust  Manchester UK"},{"name":"Department of Urology Manchester Royal Infirmary  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,18]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"SchickMA&SternardBTTesticular Torsion. Nih.gov. StatPearls Publishing2023."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2023.01.031"},{"issue":"12","key":"e_1_2_11_4_1","first-page":"835","article-title":"Testicular torsion: diagnosis, evaluation, and management","volume":"88","author":"Sharp VJ","year":"2013","journal-title":"Am Fam Physician"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.h1563"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.5534\/wjmh.190037"},{"key":"e_1_2_11_7_1","unstructured":"NICE Clinical Knowledge Summaries.Scrotal pain & swelling: Causes \u2014 testicular torsion."},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2020.07.006"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n160"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2022.09.019"},{"issue":"2","key":"e_1_2_11_12_1","first-page":"40","article-title":"Hormonal levels, semen parameters and presence of antisperm antibodies in patients treated for testicular torsion","volume":"6","author":"Al\u2010Nasiri U","year":"2010","journal-title":"New Iraqi J Med"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410x.1986.tb05916.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(17)37622-x"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.106.002097"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.04.066"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deac271"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2019.10.008"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/aja202410"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365599609182336"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.10.086"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800700409"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11216507"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(94)90090-6"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.12.057"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060520918792"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(06)00329-6"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7412.434"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(03)01866-1"},{"key":"e_1_2_11_31_1","volume-title":"WHO laboratory manual for the examination and processing of human semen","author":"World Health Organization","year":"2021"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0578.2007.00162.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dez030"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dey235"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-21-0123"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/14.4.1039"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.006908"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2010.03.006"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2015.08.002"}],"container-title":["BJUI Compass"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70287","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bco2.70287","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T05:57:03Z","timestamp":1792389423000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1002\/bco2.70287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/bco2.70287"],"URL":"https:\/\/doi.org\/10.1002\/bco2.70287","archive":["Portico"],"relation":{},"ISSN":["2688-4526","2688-4526"],"issn-type":[{"value":"2688-4526","type":"print"},{"value":"2688-4526","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70287"}}