{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:36:15Z","timestamp":1793093775988,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJUI Compass"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aims to examine how patient demographics and clinical characteristics relate to mental well\u2010being in men with prostate cancer (PCa) on active surveillance (AS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods<\/jats:title>\n                    <jats:p>\n                      We analysed data from the GAP3 database, established in 2014. The study included men from three cohorts who completed baseline self\u2010reported well\u2010being assessments using either the Memorial Anxiety Scale for Prostate Cancer (MAX\u2010PC,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009488) or the Functional Assessment of Cancer Therapy\u2013Prostate Emotional Well\u2010being Score (FACT\u2010P EWB,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009497). MAX\u2010PC scores were categorised as mild (&lt;9), moderate (9\u201327) or high anxiety (\u226527), while FACT\u2010P EWB scores were divided into tertiles (\u226418, 19\u201320 and \u226521; higher scores indicate better emotional well\u2010being). Descriptive statistics and ordinal logistic regression were used to examine associations between baseline characteristics and questionnaire scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the men across three cohorts, 488 completed the MAX\u2010PC and 497 the FACT\u2010P EWB. In the chi2 analysis for the MAX\u2010PC cohort, anxiety levels were significantly associated with baseline BMI, ethnicity, marital status, education, family history of PCa, PSA levels, T stage, smoking status, Charlson Comorbidity Index and erectile dysfunction (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Ordinal logistic regression showed that a family history of prostate cancer was associated with higher anxiety (OR\u2009=\u20091.94, 95% CI: 1.26\u20133.00). In contrast, no significant associations were observed in the FACT\u2010P EWB cohort.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings highlight several baseline demographic and clinical factors associated with disease\u2010specific anxiety in men with PCa on AS. These results underscore the importance of routine psychosocial elements and of considering lifestyle and psychosocial factors when evaluating the supportive care needs of men considering or pursuing PCa AS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bco2.70293","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:25:34Z","timestamp":1792052734000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Baseline Patient and Tumour Characteristics Associated with Mental Health in Men Undergoing Active Surveillance for Prostate Cancer"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5640-8425","authenticated-orcid":false,"given":"Beth","family":"Russell","sequence":"first","affiliation":[{"name":"Transforming Cancer Outcomes Through Research (TOUR) King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1443-856X","authenticated-orcid":false,"given":"Mia","family":"Tazi","sequence":"additional","affiliation":[{"name":"Transforming Cancer Outcomes Through Research (TOUR) King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8402-9712","authenticated-orcid":false,"given":"Harriet","family":"Wylde","sequence":"additional","affiliation":[{"name":"Transforming Cancer Outcomes Through Research (TOUR) King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Francis","sequence":"additional","affiliation":[{"name":"Transforming Cancer Outcomes Through Research (TOUR) King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8532-0251","authenticated-orcid":false,"given":"Christian P.","family":"Pavlovich","sequence":"additional","affiliation":[{"name":"Johns Hopkins School of Medicine The James Buchanan Brady Urological Institute  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Peacock","sequence":"additional","affiliation":[{"name":"University of British Columbia, BC Cancer Agency  Vancouver Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daan","family":"Nieboer","sequence":"additional","affiliation":[{"name":"Department of Urology, Erasmus MC Cancer Institute Erasmus University Medical Center  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4269-0623","authenticated-orcid":false,"given":"Lionne D. F.","family":"Venderbos","sequence":"additional","affiliation":[{"name":"Department of Urology, Erasmus MC Cancer Institute Erasmus University Medical Center  Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prokar","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Department of Urology Guy's Hospital Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7317-0858","authenticated-orcid":false,"given":"Mieke","family":"Van Hemelrijck","sequence":"additional","affiliation":[{"name":"Transforming Cancer Outcomes Through Research (TOUR) King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Cancer Research UK.Prostate cancer survival statistics[Internet]. Available from:https:\/\/www.cancerresearchuk.org\/health\u2010professional\/cancer\u2010statistics\/statistics\u2010by\u2010cancer\u2010type\/prostate\u2010cancer\/survival#:~:text=Ten\u2010year%20survival%20has%20increased as%20the%20success%20of%20treatment"},{"key":"e_1_2_10_3_1","unstructured":"GLOBOCAN.World fact sheet [Internet].2022. Available from:https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/populations\/900\u2010world\u2010fact\u2010sheet.pdf"},{"key":"e_1_2_10_4_1","unstructured":"GLOBOCAN.Europe fact sheet.2022. Available from:https:\/\/gco.iarc.who.int\/media\/globocan\/factsheets\/populations\/908\u2010europe\u2010fact\u2010sheet.pdf"},{"key":"e_1_2_10_5_1","unstructured":"Prostate Cancer UK.Active surveillance [Internet].2023. Available from:https:\/\/prostatecanceruk.org\/prostate-information-and-support\/treatments\/active-surveillance"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2015.07.025"},{"key":"e_1_2_10_7_1","unstructured":"National Institute for Health Care and Excellence.Prostate cancer: quality standard [Internet].2021. Available from:https:\/\/www.nice.org.uk\/guidance\/qs91\/chapter\/quality\u2010statement\u20104\u2010managing\u2010adverse\u2010effects\u2010of\u2010treatment#:~:text=Rationale the%20person%27s%20quality%20of%20life"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.70040"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-022-06976-w"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.10.028"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14106"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11386"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-020-00279-z"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00459-7"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2022.09.001"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2014.11.001"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2022.01.042"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euo.2021.10.004"}],"container-title":["BJUI Compass"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70293","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bco2.70293","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bco2.70293","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:06:01Z","timestamp":1793091961000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1002\/bco2.70293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/bco2.70293"],"URL":"https:\/\/doi.org\/10.1002\/bco2.70293","archive":["Portico"],"relation":{},"ISSN":["2688-4526","2688-4526"],"issn-type":[{"value":"2688-4526","type":"print"},{"value":"2688-4526","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2025-11-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70293"}}