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One such example is neck\u2010vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections. Although spaceflight has not previously been associated with thromboembolic events, recent cases of neck\u2010vein thrombosis in astronauts aboard the International Space Station have raised concern. These events were detected incidentally and showed no obvious symptoms, complicating diagnosis. Retrospective studies have not found consistent biomarkers indicating a hypercoagulable state in space, but environmental factors such as weightlessness\u2010induced venous stasis and potential endothelial damage may contribute. Oral contraceptives could promote thrombotic risk in female astronauts, although no direct link has been confirmed. Research on terrestrial models simulating space conditions has not yet provided conclusive insights into thrombosis prevention. 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