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This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic\u2010informed care, or that measure the impact of pharmacogenetic\u2010informed care on psychological factors that are associated with medication adherence. Adherence\u2010related psychological factors are mapped to the Theoretical Domains Framework (TDF) to provide insight into how participants interact with pharmacogenetic\u2010informed care as an intervention and to consider this in the context of medication adherence. A total of 23 studies were included, with 10 quantitative studies measuring medication adherence outcomes associated with pharmacogenetic\u2010informed care. Five of these studies found a statistically significant improvement in adherence in the pharmacogenetic\u2010tested group, two reported a small but non\u2010significant trend, and three showed no difference. Additionally, 13 studies examined the impact of pharmacogenetic\u2010informed care on psychological factors related to adherence. These factors were mapped to 10 TDF domains: knowledge (8 studies); social\/professional role and identity (1); beliefs about capabilities (2); optimism (4); beliefs about consequences (10); intentions (5); goals (1); memory, attention and decision processes (7); social influences (4); and emotion (8). The findings suggest that although the evidence for pharmacogenetic\u2010informed care improving medication adherence is mixed and limited, pharmacogenetic\u2010informed care appears to positively influence psychological factors that may support adherence. These include improving knowledge, supporting decision\u2010making and generally being perceived as a positive experience by patients.<\/jats:p>","DOI":"10.1002\/bcp.70800","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:20:57Z","timestamp":1789615257000},"source":"Crossref","is-referenced-by-count":0,"title":["The impact of pharmacogenetic\u2010informed care on medication adherence and psychological factors associated with adherence: A narrative review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8396-7855","authenticated-orcid":false,"given":"Lucy","family":"Galloway","sequence":"first","affiliation":[{"name":"Institute of Pharmaceutical Sciences King's College London  London UK"},{"name":"NHS South East Genomic Medicine Service St George's University Hospitals NHS Foundation Trust  London 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