{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T18:10:02Z","timestamp":1699726202536},"reference-count":3,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T00:00:00Z","timestamp":1136937600000},"content-version":"vor","delay-in-days":9507,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biopharm &amp; Drug Disp"],"published-print":{"date-parts":[[1980,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A simple, rapid, and sensitive procedure is described for the determination of Fendosal in plasma. After extraction of Fendosal from buffered plasma, the drug is determined by measurement of the fluorescence induced by irradiation with short\u2010wave ultra\u2010violet (UV) light. The complete procedure can be completed in less than 2 h; one technician can perform up to 50 assays in one working day. The limit of detection corresponds to 0\u20131 \u03bcg ml<jats:sup>\u22121<\/jats:sup> plasma. Drug concentration and induced fluorescence were linearly related over the concentration range 0\u20138 \u03bcg ml<jats:sup>\u22121<\/jats:sup>.<\/jats:p>","DOI":"10.1002\/bdd.2510010302","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T13:42:43Z","timestamp":1160833363000},"page":"97-102","source":"Crossref","is-referenced-by-count":2,"title":["Rapid fluorimetric procedure for the analysis of Fendosal in plasma and data following oral dosing"],"prefix":"10.1002","volume":"1","author":[{"given":"H. M.","family":"Hill","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Chamberlain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Hajdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Damm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,11]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"2141","article-title":"\u201cEine neue fluorimetrische Methode zur Bestimmung von Phar\u2010maka in biologischem Material\u201d","volume":"26","author":"Hajdu P.","year":"1976","journal-title":"Arzn. Forschung"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm00224a023"},{"key":"e_1_2_1_4_2","unstructured":"G. J.Yakatan R. B.Smith A. H.BriggsandJ. T.Doluisio(unpublished work)."}],"container-title":["Biopharmaceutics &amp; Drug Disposition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdd.2510010302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdd.2510010302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,11]],"date-time":"2023-11-11T17:28:02Z","timestamp":1699723682000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdd.2510010302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,1]]},"references-count":3,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,1]]}},"alternative-id":["10.1002\/bdd.2510010302"],"URL":"https:\/\/doi.org\/10.1002\/bdd.2510010302","archive":["Portico"],"relation":{},"ISSN":["0142-2782","1099-081X"],"issn-type":[{"value":"0142-2782","type":"print"},{"value":"1099-081X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,1]]}}}