{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T20:59:00Z","timestamp":1769633940580,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,2,7]],"date-time":"2006-02-07T00:00:00Z","timestamp":1139270400000},"content-version":"vor","delay-in-days":5060,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biopharm &amp; Drug Disp"],"published-print":{"date-parts":[[1992,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to evaluate the dietary caffeine and dimethylxanthine concentrations in breast milk of 40 mothers from different ethnic and socioeconomic backgrounds. Their diets and drug intake were not restricted in any way. Each nursing mother provided a fasting and a combined breast\u2010milk sample each day for 3 consecutive days. No significant differences were found in intake levels of any of the methylxanthines among the groups tested. No significant differences were found among the four groups in breast\u2010milk levels of caffeine, theobromine, or paraxanthine. However, the mean theophylline milk levels were significantly higher on 2 of the 3 days examined in Anglo\u2010American woman compared to Hispanic\u2010American women. Socioeconomic and ethnic variables were also compared among the four groups. The daily amounts of methylxanthines found in the breast milk of this free\u2010living population of mothers do not appear to present clinically significant amounts to the infant.<\/jats:p>","DOI":"10.1002\/bdd.2510130305","type":"journal-article","created":{"date-parts":[[2006,10,14]],"date-time":"2006-10-14T13:00:39Z","timestamp":1160830839000},"page":"187-196","source":"Crossref","is-referenced-by-count":12,"title":["Methylxanthine levels in breast milk of lactating women of different ethnic and socioeconomic classes"],"prefix":"10.1002","volume":"13","author":[{"given":"James","family":"Blanchard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles W.","family":"Webr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luz\u2010E.","family":"Shearer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1542\/peds.71.2.166","volume":"71","author":"Martinez G. A.","year":"1983","journal-title":"Pediatrics"},{"key":"e_1_2_1_3_2","unstructured":"Office of Disease Prevention and Health Promotion Disease Prevention\/Health Promotion\u2014The Facts U. S. Department of Health and Human Services Bethesda Maryland 1988."},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-6915(88)90007-5"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-6915(88)90236-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0278-6915(88)90073-7"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000457057"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1983.80"},{"key":"e_1_2_1_9_2","volume-title":"Evrydiet: A Nutrition and Diet Guide","author":"Garguilo J.","year":"1983"},{"key":"e_1_2_1_10_2","volume-title":"Physician's Desk Reference","year":"1983"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1978.tb03717.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0002-8223(21)39775-9","volume":"74","author":"Bunker M. L.","year":"1979","journal-title":"J. Am. Diet. Assoc."},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2621.1984.tb13737.x"},{"key":"e_1_2_1_14_2","first-page":"14","volume":"3","author":"Lecos C.","year":"1984","journal-title":"FDA Consumer"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/chromsci\/28.12.640"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.54.10.787"},{"key":"e_1_2_1_17_2","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1542\/peds.57.4.518","volume":"57","author":"Yurchak A. M.","year":"1976","journal-title":"Pediatrics"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1542\/peds.73.1.59","volume":"73","author":"Berlin C. M.","year":"1984","journal-title":"Pediatrics"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)81329-2"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-6147(91)90516-U"},{"key":"e_1_2_1_21_2","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1542\/peds.81.3.365","volume":"81","author":"Kurinij N.","year":"1988","journal-title":"Pediatrics"},{"key":"e_1_2_1_22_2","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1542\/peds.82.3.496","volume":"82","author":"Wright A. L.","year":"1988","journal-title":"Pediatrics"},{"key":"e_1_2_1_23_2","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1093\/ajcn\/50.4.868","volume":"50","author":"John A. M.","year":"1989","journal-title":"Am. J. Clin. Nutr."},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/000992289002900207"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80370-4"},{"key":"e_1_2_1_26_2","first-page":"370","volume":"5","author":"Nelson R. M.","year":"1981","journal-title":"Semin. Perinatol."},{"key":"e_1_2_1_27_2","first-page":"389","volume":"5","author":"Berlin C. M.","year":"1981","journal-title":"Semin. Perinatol."},{"key":"e_1_2_1_28_2","first-page":"868","volume-title":"Proc Second World Conf Clin Pharmacol Ther","author":"Aranda J. V.","year":"1984"},{"key":"e_1_2_1_29_2","first-page":"371","volume":"34","author":"Tang\u2010Liu DD\u2010S.","year":"1981","journal-title":"Res. Commun. Chem. Pathol. Pharmacol"},{"key":"e_1_2_1_30_2","first-page":"119","volume-title":"Drug Therapy in Infants, Pharmacologic Principles and Clinical Experience","author":"Roberts R. J.","year":"1984"},{"key":"e_1_2_1_31_2","first-page":"924","article-title":"American Academy of Pediatrics, Committee on Drugs","volume":"84","year":"1989","journal-title":"Pediatrics"}],"container-title":["Biopharmaceutics &amp; Drug Disposition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdd.2510130305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdd.2510130305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T10:26:04Z","timestamp":1698056764000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdd.2510130305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,4]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,4]]}},"alternative-id":["10.1002\/bdd.2510130305"],"URL":"https:\/\/doi.org\/10.1002\/bdd.2510130305","archive":["Portico"],"relation":{},"ISSN":["0142-2782","1099-081X"],"issn-type":[{"value":"0142-2782","type":"print"},{"value":"1099-081X","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,4]]}}}