{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T13:00:27Z","timestamp":1726405227791},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2002,2,21]],"date-time":"2002-02-21T00:00:00Z","timestamp":1014249600000},"content-version":"vor","delay-in-days":82,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biopharm &amp; Drug Disp"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to determine interaction of smoking with single dose pharmacokinetics of phenobarbital, a 60 mg tablet of the drug was given to 12 healthy male subjects in two groups (6 smokers and 6 non\u2010smokers) in a double blind study. An HPLC method using UV detection was developed to assess phenobarbital in plasma of the subjects. Pharmacokinetic parameters were calculated and compared in the two groups. Pharmacokinetic parameters of the two groups were not significantly different in the two groups (<jats:italic>p<\/jats:italic>&lt;0.05). The results show no considerable effect of cigarette smoking on phenobarbital pharmacokinetics, which is in agreement with enzyme studies performed previously. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/bdd.284","type":"journal-article","created":{"date-parts":[[2005,1,24]],"date-time":"2005-01-24T07:46:41Z","timestamp":1106552801000},"page":"403-406","source":"Crossref","is-referenced-by-count":3,"title":["Effect of smoking on single dose pharmacokinetics of phenobarbital"],"prefix":"10.1002","volume":"22","author":[{"given":"A.","family":"Mirfazaelian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Jahanzad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tabatabaei\u2010far","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Farsam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mahmoudian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,2,21]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"376","volume-title":"The Goodman & Gilman's Pharmacological Basis of Therapeutics","author":"Hobbs WR","year":"1996"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1985.tb02800.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600730414"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1982.tb02662.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(75)90503-2"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1976195part1546"},{"key":"e_1_2_1_8_2","first-page":"17","article-title":"The influence of cigarette smoking and sex on theophylline disposition","volume":"116","author":"Powell JR","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_1_9_2","first-page":"229","volume-title":"Pharmacokinetics of Psychoactive Drugs","author":"Perel JM","year":"1976"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpt19792618"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01721923"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198712040-00004"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198917020-00003"},{"key":"e_1_2_1_14_2","first-page":"125","article-title":"Cigarettes and drug therapy: pharmacokinetic and pharmacodynamic considerations","volume":"9","author":"Miller LG","year":"1990","journal-title":"Clin Pharm"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(76)90300-4"},{"key":"e_1_2_1_16_2","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1093\/clinchem\/29.3.473","article-title":"Simultaneous very fast liquid\u2010chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum","volume":"29","author":"Kabra PM","year":"1983","journal-title":"Clin Chem"},{"key":"e_1_2_1_17_2","unstructured":"MirfazaelianA MahmoudianM.A comprehensive computer programme for evaluation and teaching drug pharmacokinetics. Abstr 12th Iranian Congr Physiology and Pharmacology Paper1995; P3\u201018."},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2710.1998.00086.x"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1977225part2749"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5173(79)90061-9"},{"key":"e_1_2_1_21_2","first-page":"78","volume-title":"Cytochrome P450 Metabolic and Toxicological Aspects","author":"Kawajiri K","year":"1996"},{"key":"e_1_2_1_22_2","first-page":"1","volume-title":"Cytochrome P450, Structure, Function and Mechanism","author":"Lewis","year":"1996"}],"container-title":["Biopharmaceutics &amp; Drug Disposition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdd.284","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdd.284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T16:09:47Z","timestamp":1700410187000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdd.284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1002\/bdd.284"],"URL":"https:\/\/doi.org\/10.1002\/bdd.284","archive":["Portico"],"relation":{},"ISSN":["0142-2782","1099-081X"],"issn-type":[{"type":"print","value":"0142-2782"},{"type":"electronic","value":"1099-081X"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}