{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T16:09:18Z","timestamp":1764605358801,"version":"3.46.0"},"reference-count":4,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Biopharm &amp; Drug Disp"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This letter responds to a recent review on nasal drug delivery systems for brain\u2010targeted therapy. Drawing on first hand experiences as a psychiatrist and migraine patient in Taiwan, the response discusses the practical benefits and challenges of using nasal formulations, such as sumatriptan nasal spray, during ongoing drug shortages. While these formulations offer rapid onset of action, issues related to taste and odor can limit adherence. The letter highlights the potential of advanced technologies like nanocarriers to improve nasal drug delivery and emphasizes the need for patient\u2010centered designs. The correspondence concludes with recommendations for diversifying drug delivery approaches to enhance efficacy and accessibility.<\/jats:p>","DOI":"10.1002\/bdd.70013","type":"journal-article","created":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T04:29:57Z","timestamp":1756182597000},"page":"163-164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Role of Nasal Drug Delivery in Migraine Management and Brain\u2010Targeted Therapy: Insights From Taiwan"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7383-7309","authenticated-orcid":false,"given":"Lien\u2010Chung","family":"Wei","sequence":"first","affiliation":[{"name":"Department of Addiction Psychiatry Taoyuan Psychiatric Center Ministry of Health and Welfare  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsien\u2010Jane","family":"Chiu","sequence":"additional","affiliation":[{"name":"Department of Counseling and Industrial\/Organizational Psychology Ming Chuan University  Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2400"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20318"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201006565"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201701921"}],"container-title":["Biopharmaceutics &amp; Drug Disposition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdd.70013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T16:06:44Z","timestamp":1764605204000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdd.70013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":4,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/bdd.70013"],"URL":"https:\/\/doi.org\/10.1002\/bdd.70013","archive":["Portico"],"relation":{},"ISSN":["0142-2782","1099-081X"],"issn-type":[{"type":"print","value":"0142-2782"},{"type":"electronic","value":"1099-081X"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2024-12-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}