{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:10:05Z","timestamp":1773706205795,"version":"3.50.1"},"reference-count":76,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006457","name":"Child Neurology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006457","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2019,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Mothers need a nutrient\u2010rich diet for healthy neural tube development. Neural tube defect risk can be reduced through fortifying grain products with folic acid and taking folic acid supplements. Fortification is not required in Bangladesh. Maternal supplement use rates are low, similar to other countries. This study evaluates maternal dietary intake during pregnancy to identify possible interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A food frequency questionnaire (FFQ) assessed maternal diet. The primary aim compared dietary intake (calories, fat, carbohydrate, protein, fiber, vitamins, and minerals) between mothers of infants with myelomeningocele (cases) and mothers of controls. Secondary aims included (i) comparing foods consumed and (ii) evaluating if rice intake correlated with arsenic exposure. Paired<jats:italic>t<\/jats:italic>\u2010tests, Wilcoxon signed rank tests, McNemar's chi\u2010squared test, and linear regression were used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 110 matched mother\u2013infant pairs (55 cases\/55 controls). Mothers of cases and mothers of controls had similar caloric intake [median 2406 kcal\/day vs. 2196 kcal\/day (<jats:italic>p<\/jats:italic>\u2009=\u20090.071)]. Mothers in both groups consumed less than half the daily recommended 600 \u03bcg of folate. Diets were potentially deficient in vitamins A, D, E, potassium, sodium, and iron. Steamed rice was the primary food consumed for both groups, and this rice intake was not associated with toenail arsenic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dietary interventions should increase folate, vitamins A, D, E, potassium, sodium, and iron intake in Bangladeshi mothers. Folic acid fortification of grain products maybe the only viable strategy to achieve adequate folate intake for mothers. Given the central role of rice to the Bangladeshi diet, fortifying rice may be a viable option.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.1505","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T05:10:42Z","timestamp":1555391442000},"page":"967-981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["A case\u2013control analysis of maternal diet and risk of neural tube defects in Bangladesh"],"prefix":"10.1002","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4450-9194","authenticated-orcid":false,"given":"John F.","family":"Obrycki","sequence":"first","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4967-1115","authenticated-orcid":false,"given":"Jane J.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kush","family":"Kapur","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ligi","family":"Paul","sequence":"additional","affiliation":[{"name":"Jean Mayer United States Department of Agriculture (USDA) Human Nutrition Research Center on Aging Tufts University Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Omar Sharif Ibne","family":"Hasan","sequence":"additional","affiliation":[{"name":"Dhaka Community Hospital Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selim","family":"Mia","sequence":"additional","affiliation":[{"name":"Dhaka Community Hospital Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quazi","family":"Quamruzzaman","sequence":"additional","affiliation":[{"name":"Dhaka Community Hospital Dhaka Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David C.","family":"Christiani","sequence":"additional","affiliation":[{"name":"Department of Environmental Health Harvard T.H. Chan School of Public Health Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maitreyi","family":"Mazumdar","sequence":"additional","affiliation":[{"name":"Department of Neurology Boston Children's Hospital Boston Massachusetts"},{"name":"Department of Environmental Health Harvard T.H. Chan School of Public Health Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23100"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-010-0106-y"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2015.302902"},{"key":"e_1_2_8_5_1","volume-title":"Child and mother nutrition survey 2012","author":"Bangladesh Bureau of Statistics","year":"2013"},{"issue":"1","key":"e_1_2_8_6_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: A practical and powerful approach to multiple testing","volume":"57","author":"Benjamini Y.","year":"1995","journal-title":"Journal of the Royal Statistical Society: Series B"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqy148"},{"key":"e_1_2_8_8_1","volume-title":"British Geological Survey technical report WC\/00\/19","author":"British Geological Survey and Department of Public Health Engineering(Bangladesh)","year":"2001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/137.9.2087"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20675"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpediatrics.2011.185"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2003.07.009"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.20230"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980012003576"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02784067"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20041277"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.5.1224"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwk037"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.04.041"},{"key":"e_1_2_8_20_1","volume-title":"March of dimes global report on birth defects: The hidden toll of dying and disabled children","author":"Christianson A.","year":"2006"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70110-8"},{"key":"e_1_2_8_22_1","volume-title":"Method 200.8, revision 5.4: Determination of trace elements in waters and wastes by inductively coupled plasma\u2010mass spectrometry","author":"Creed J. T.","year":"1994"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11010071"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199212243272602"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20485"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdr2.1198"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0170199"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.6.1372"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8084"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.5.1093"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287399009531407"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2010.300090"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12699"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.12.032"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.6.1516"},{"key":"e_1_2_8_36_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.47102\/annals-acadmedsg.V33N4p31S","article-title":"Epidemiology of betel quid usage","volume":"33","author":"Gupta P.","year":"2004","journal-title":"Annals of the Academy of Medicine, Singapore"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2011.00314.x"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2014.07.075"},{"key":"e_1_2_8_39_1","first-page":"980","volume-title":"Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects","author":"Hewitt S. M.","year":"1992"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1972.10666051"},{"key":"e_1_2_8_41_1","volume-title":"Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, panthothenic acid, biotin, and choline","author":"Institute of Medicine","year":"1998"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.111.013433"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0188726"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28350"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.108.101022"},{"key":"e_1_2_8_46_1","volume-title":"moments: Moments, cumulants, skewness, kurtosis and related tests. R package version 0.14","author":"Komsta L","year":"2015"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-12-ED1"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23236"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1110(80)90027-5"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/51.1.98"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-015-0020-0"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23399"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90133-A"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/geh036"},{"key":"e_1_2_8_55_1","doi-asserted-by":"crossref","first-page":"2326","DOI":"10.3945\/jn.117.257303","article-title":"Integrating nutrition interventions into an existing maternal, neonatal, and child health program increased maternal dietary diversity, micronutrient intake, and exclusive breastfeeding practices in Bangladesh: Results of a cluster\u2010randomized program evaluation","volume":"147","author":"Nguyen P. H.","year":"2017","journal-title":"The Journal of Nutrition"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23538"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxy090"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.2188\/jea.JE2007417"},{"key":"e_1_2_8_59_1","volume-title":"Nutrient recommendations: Dietary reference intakes (DRI)","author":"Office of Dietary Supplements"},{"key":"e_1_2_8_60_1","volume-title":"Iron fact sheet for health professionals","author":"Office of Dietary Supplements","year":"2018"},{"key":"e_1_2_8_61_1","volume-title":"Potassium fact sheet for health professionals","author":"Office of Dietary Supplements","year":"2018"},{"key":"e_1_2_8_62_1","volume-title":"Vitamin A fact sheet for health professionals","author":"Office of Dietary Supplements","year":"2018"},{"key":"e_1_2_8_63_1","volume-title":"Vitamin D fact sheet for health professionals","author":"Office of Dietary Supplements","year":"2018"},{"key":"e_1_2_8_64_1","volume-title":"Vitamin E fact sheet for health professionals","author":"Office of Dietary Supplements","year":"2018"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq366"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11872"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00115.x"},{"key":"e_1_2_8_68_1","volume-title":"Food composition table for Bangladesh","author":"Shaheen N.","year":"2013"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/07399330802269493"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/mcn.12532"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592294.2017.1312238"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2018.05.023"},{"key":"e_1_2_8_73_1","volume-title":"USDA food Compostion databases","author":"USDA","year":"2018"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gfs.2017.09.003"},{"key":"e_1_2_8_75_1","first-page":"1","article-title":"Updated estimates of neural tube defects prevented by mandatory folic acid fortification\u2010United States, 1995\u20132011","volume":"64","author":"Williams J.","year":"2015","journal-title":"MMWR. Morbidity and Mortality Weekly Report"},{"key":"e_1_2_8_76_1","first-page":"1S","article-title":"Folate and vitamin B\u201012 biomarkers in NHANES: History of their measurement and use","volume":"94","author":"Yetley E. A.","year":"2011","journal-title":"The American Journal of Clinical Nutrition"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-011-1492-8"}],"container-title":["Birth Defects Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdr2.1505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.1505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bdr2.1505","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.1505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T23:03:14Z","timestamp":1721170994000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdr2.1505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,15]]},"references-count":76,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2019,8,15]]}},"alternative-id":["10.1002\/bdr2.1505"],"URL":"https:\/\/doi.org\/10.1002\/bdr2.1505","archive":["Portico"],"relation":{},"ISSN":["2472-1727","2472-1727"],"issn-type":[{"value":"2472-1727","type":"print"},{"value":"2472-1727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,15]]},"assertion":[{"value":"2018-03-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}