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Prenatal screening is available for a variety of genetic conditions including aneuploidy, congenital abnormalities, and carrier status. Diagnostic testing options include karyotype, prenatal microarray, as well as next\u2010generation sequencing. The various options differ in methodology, accuracy, timing and indication for testing, and information they provide. Given that the technologies related to prenatal testing are rapidly evolving and improving, the array of available screening and testing modalities are increasing. This article reviews the current offerings in prenatal screening and diagnosis.<\/jats:p>","DOI":"10.1002\/bdr2.1598","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T10:40:23Z","timestamp":1571654423000},"page":"321-331","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Current landscape of prenatal genetic screening and testing"],"prefix":"10.1002","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0819-9803","authenticated-orcid":false,"given":"Nevena","family":"Krsti\u0107","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University of South Florida, Morsani College of Medicine  Tampa Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah G.","family":"Obi\u010dan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of South Florida, Morsani College of Medicine  Tampa Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,10,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5038"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12364"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.14636"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.31711"},{"key":"e_1_2_8_6_1","unstructured":"American College of Obstetricians and Gynecologists. 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