{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:46:10Z","timestamp":1790711170850,"version":"4.1.0"},"reference-count":315,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01DE026737"],"award-info":[{"award-number":["R01DE026737"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01NS102261"],"award-info":[{"award-number":["R01NS102261"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01DE0221696"],"award-info":[{"award-number":["R01DE0221696"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011781","name":"Shriners Hospitals for Children","doi-asserted-by":"publisher","award":["85105"],"award-info":[{"award-number":["85105"]}],"id":[{"id":"10.13039\/100011781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>During craniofacial development, defective growth and fusion of the upper lip and\/or palate can cause orofacial clefts (OFCs), which are among the most common structural birth defects in humans. The developmental basis of OFCs includes morphogenesis of the upper lip, primary palate, secondary palate, and other orofacial structures, each consisting of diverse cell types originating from all three germ layers: the ectoderm, mesoderm, and endoderm. Cranial neural crest cells and orofacial epithelial cells are two major cell types that interact with various cell lineages and play key roles in orofacial development. The cellular basis of OFCs involves defective execution in any one or several of the following processes: neural crest induction, epithelial\u2010mesenchymal transition, migration, proliferation, differentiation, apoptosis, primary cilia formation and its signaling transduction, epithelial seam formation and disappearance, periderm formation and peeling, convergence and extrusion of palatal epithelial seam cells, cell adhesion, cytoskeleton dynamics, and extracellular matrix function. The latest cellular and developmental findings may provide a basis for better understanding of the underlying genetic, epigenetic, environmental, and molecular mechanisms of OFCs.<\/jats:p>","DOI":"10.1002\/bdr2.1768","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T07:35:57Z","timestamp":1596008157000},"page":"1558-1587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Cellular and developmental basis of orofacial clefts"],"prefix":"10.1002","volume":"112","author":[{"given":"Yu","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"},{"name":"Biochemistry, Molecular, Cellular, and Developmental Biology (BMCDB) graduate group University of California  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Garland","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"},{"name":"Biochemistry, Molecular, Cellular, and Developmental Biology (BMCDB) graduate group University of California  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moira","family":"McMahon","sequence":"additional","affiliation":[{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratheya","family":"Rajakumar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad S.","family":"Islam","sequence":"additional","affiliation":[{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"YiPing","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cell and Molecular Biology Tulane University  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8592-4680","authenticated-orcid":false,"given":"Chengji J.","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Medicine University of California at Davis, School of Medicine  Sacramento California USA"},{"name":"Institute for Pediatric Regenerative Medicine of Shriners Hospitals for Children, School of Medicine University of California at Davis  Sacramento California USA"},{"name":"Biochemistry, Molecular, Cellular, and Developmental Biology (BMCDB) graduate group University of California  Davis California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.24338"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/joa.12291"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(83)90167-X"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2004.09.010"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-015-1531-z"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgu194"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00698"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.5772\/62519"},{"issue":"19","key":"e_1_2_12_10_1","doi-asserted-by":"crossref","first-page":"4647","DOI":"10.1242\/dev.129.19.4647","article-title":"Endogenous bone morphogenetic proteins regulate outgrowth and epithelial survival during avian lip fusion","volume":"129","author":"Ashique A. M.","year":"2002","journal-title":"Development"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav9996"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10142-019-00659-2"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.genom.7.080505.115610"},{"issue":"2","key":"e_1_2_12_14_1","first-page":"167","article-title":"Relative growth rates of maxillary mesenchyme in the chick embryo","volume":"8","author":"Bailey L. J.","year":"1988","journal-title":"Journal of Craniofacial Genetics and Developmental Biology"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2009.10.010"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-009-0834-6"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.174"},{"issue":"7","key":"e_1_2_12_18_1","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1242\/dev.129.7.1583","article-title":"Overexpression of snail family members highlights their ability to promote chick neural crest formation","volume":"129","author":"Barrio M. G.","year":"2002","journal-title":"Development"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2012.10.011"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2006.043687"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.177725.114"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.12.5.1457"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(02)00361-7"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200103069"},{"key":"e_1_2_12_25_1","first-page":"111","article-title":"Cell distribution during mouse secondary palate closure. II. Mesenchymal cells","volume":"96","author":"Brinkley L. L.","year":"1986","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910208101206"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq030"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33727"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.005132"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(05)73001-5"},{"issue":"2","key":"e_1_2_12_31_1","first-page":"345","article-title":"Inhibition of TGF\u2010beta 3 (but not TGF\u2010beta 1 or TGF\u2010beta 2) activity prevents normal mouse embryonic palate fusion","volume":"39","author":"Brunet C. L.","year":"1995","journal-title":"The International Journal of Developmental Biology"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-051309-103849"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001200112"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004270050161"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.067082"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.10.050"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.114.2.379"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2003.00498.x"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.10.024"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20821"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20522"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2009.069468"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81732-8"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20833"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199704)208:4<526::AID-AJA8>3.0.CO;2-K"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.4161\/cam.4.3.12138"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/cge.13465"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00392"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38106.559120.7C"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-016-1033-x"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2010.09.013"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2009.09.002"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04117"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33702"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/wdev.199"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.114.1.1"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.117.2.409"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0009-9163.2004.00225.x"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.22.010305.103814"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980827)79:1<42::AID-AJMG11>3.0.CO;2-M"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00907"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2002.0620"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10326"},{"issue":"6","key":"e_1_2_12_64_1","first-page":"817","article-title":"Immunohistochemical localization of TGF\u2010beta type II receptor and TGF\u2010beta3 during palatogenesis in vivo and in vitro","volume":"42","author":"Cui X. M.","year":"1998","journal-title":"The International Journal of Developmental Biology"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3722"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2009.04.016"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.25.6.427"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01857"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(01)00484-5"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(68)90138-6"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.9.6.1425"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21205"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2013.130"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0603730103"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2006.05.030"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2006.05.009"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2003.10.007"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13630-017-0051-y"},{"key":"e_1_2_12_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2010.06.002"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/jdb4030024"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.23.090506.123249"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.050591"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000164494.45986.91"},{"key":"e_1_2_12_84_1","first-page":"1","article-title":"Induction of cleft lip in cultured rat embryos by localized administration of tunicamycin","volume":"64","author":"Eto K.","year":"1981","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar3131"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.103.Supplement.41"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1684"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2011.08.005"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0012-1606(89)80017-X"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08908"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13630-016-0034-4"},{"key":"e_1_2_12_92_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2005.031385"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20564"},{"key":"e_1_2_12_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001500308"},{"key":"e_1_2_12_95_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001500307"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(02)00823-7"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.891"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-0436.1992.tb00664.x"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.03.023"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2007.12"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-185X.1951.tb00774.x"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-0436.2003.710304.x"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.2001.19910133.x"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.10980"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099320"},{"issue":"2","key":"e_1_2_12_106_1","first-page":"225","article-title":"Developmental aspects of secondary palate formation","volume":"36","author":"Greene R. M.","year":"1976","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004381"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.116.4.1087"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2017.03.001"},{"key":"e_1_2_12_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.09.012"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(76)90259-1"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0010053"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.641670"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-70754-4_1"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1054\/jcms.2002.0323"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.026229"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-014-9727-2"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a027904"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1903"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a021998"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01806.x"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1190304"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8101173"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.20646"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.7.1046"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.05.015"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02520"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.075796"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2020.01.026"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1725"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1002\/neu.20162"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2017.44"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0177(199707)209:3<255::AID-AJA1>3.0.CO;2-H"},{"key":"e_1_2_12_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1295-415"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10161"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0544.2003.02236.x"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1600060"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.04.036"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells5010006"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12962"},{"issue":"1","key":"e_1_2_12_141_1","first-page":"93","article-title":"Meckel\u2010Gruber syndrome: A rare and lethal anomaly","volume":"12","author":"Kheir A. E.","year":"2012","journal-title":"Sudanese Journal of Paediatrics"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2006.01.011"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1002122"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0201"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.120117yk"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-46954-6_7"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1290\/1543-706X(2003)039<0098:HOAAAP>2.0.CO;2"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1038\/13031"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng985"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-019-0383-x"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1038\/368703a0"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ctdb.2015.07.002"},{"issue":"1","key":"e_1_2_12_153_1","first-page":"125","article-title":"Mesenchymal derivatives of the neural crest: Analysis of chimaeric quail and chick embryos","volume":"34","author":"Le Lievre C. S.","year":"1975","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07604-0"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/0248-4900(88)90058-5"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23076"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420090114"},{"key":"e_1_2_12_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2007.04.005"},{"key":"e_1_2_12_159_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23026"},{"key":"e_1_2_12_160_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514534444"},{"key":"e_1_2_12_161_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.174888"},{"key":"e_1_2_12_162_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.29061"},{"key":"e_1_2_12_163_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.24263"},{"key":"e_1_2_12_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.regen.2020.100029"},{"key":"e_1_2_12_165_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.157628"},{"key":"e_1_2_12_166_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517726284"},{"issue":"4","key":"e_1_2_12_167_1","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1242\/dev.113.4.1281","article-title":"Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo","volume":"113","author":"Lumsden A.","year":"1991","journal-title":"Development"},{"key":"e_1_2_12_168_1","doi-asserted-by":"publisher","DOI":"10.1159\/000146662"},{"key":"e_1_2_12_169_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569(2001)038<0379:QOLIAW>2.0.CO;2"},{"key":"e_1_2_12_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(08)00801-6"},{"key":"e_1_2_12_171_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9644"},{"key":"e_1_2_12_172_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201011077"},{"issue":"3","key":"e_1_2_12_173_1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1242\/dev.121.3.767","article-title":"Induction of the prospective neural crest of Xenopus","volume":"121","author":"Mayor R.","year":"1995","journal-title":"Development"},{"key":"e_1_2_12_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.06.022"},{"key":"e_1_2_12_175_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034508327868"},{"key":"e_1_2_12_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.03.015"},{"key":"e_1_2_12_177_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.127.17.3815"},{"key":"e_1_2_12_178_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001640104"},{"issue":"1","key":"e_1_2_12_179_1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1242\/dev.63.1.53","article-title":"Active role of embryonic facial epithelium: New evidence of cellular events in morphogenesis","volume":"63","author":"Millicovsky G.","year":"1981","journal-title":"Development"},{"key":"e_1_2_12_180_1","first-page":"65","article-title":"Cell proliferation and cell density of mesenchyme in the maxillary process and adjacent regions during facial development in the chick embryo","volume":"46","author":"Minkoff R.","year":"1978","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_181_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20170453"},{"key":"e_1_2_12_182_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3233(05)70013-9"},{"issue":"1","key":"e_1_2_12_183_1","first-page":"1","article-title":"Detailed staging of inbred C57BL\/6 mice between Theiler's [1972] stages 18 and 21 (11\u201013\u2009days of gestation) based on craniofacial development","volume":"16","author":"Miyake T.","year":"1996","journal-title":"Journal of Craniofacial Genetics and Developmental Biology"},{"issue":"3","key":"e_1_2_12_184_1","first-page":"317","article-title":"Characterization of desmosomal component expression during palatogenesis","volume":"44","author":"Mogass M.","year":"2000","journal-title":"The International Journal of Developmental Biology"},{"key":"e_1_2_12_185_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00531"},{"key":"e_1_2_12_186_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI40267"},{"key":"e_1_2_12_187_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.15971"},{"key":"e_1_2_12_188_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-10-89"},{"issue":"14","key":"e_1_2_12_189_1","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1242\/dev.124.14.2751","article-title":"The role in neural patterning of translation initiation factor eIF4AII; induction of neural fold genes","volume":"124","author":"Morgan R.","year":"1997","journal-title":"Development"},{"key":"e_1_2_12_190_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00185843"},{"key":"e_1_2_12_191_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2005.00475.x"},{"key":"e_1_2_12_192_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004290000098"},{"key":"e_1_2_12_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60695-4"},{"key":"e_1_2_12_194_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034511402083"},{"issue":"1","key":"e_1_2_12_195_1","first-page":"53","article-title":"The development of the palate\u2010a brief review","volume":"7","author":"Moxham B.","year":"2003","journal-title":"European Journal of Anatomy"},{"key":"e_1_2_12_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.03.053"},{"key":"e_1_2_12_197_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19113638"},{"key":"e_1_2_12_198_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10735-010-9296-0"},{"key":"e_1_2_12_199_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.710111"},{"key":"e_1_2_12_200_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200306024"},{"key":"e_1_2_12_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2004.05.007"},{"key":"e_1_2_12_202_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07753"},{"key":"e_1_2_12_203_1","first-page":"105","article-title":"Neural crest formation in the head of the mouse embryo as observed using a new histological technique","volume":"64","author":"Nichols D. H.","year":"1981","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(78)90201-4"},{"key":"e_1_2_12_205_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001680302"},{"key":"e_1_2_12_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(83)90318-4"},{"key":"e_1_2_12_207_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1242\/dev.103.Supplement.121","article-title":"Interactions and fates of avian craniofacial mesenchyme","volume":"103","author":"Noden D. M.","year":"1988","journal-title":"Development"},{"key":"e_1_2_12_208_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.009340"},{"issue":"5","key":"e_1_2_12_209_1","first-page":"556","article-title":"Guide to the staging of human embryos","volume":"130","author":"O'rahilly R.","year":"1972","journal-title":"Anatomischer Anzeiger"},{"key":"e_1_2_12_210_1","doi-asserted-by":"publisher","DOI":"10.1369\/0022155411427059"},{"key":"e_1_2_12_211_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-015-0150-4"},{"issue":"7","key":"e_1_2_12_212_1","first-page":"S11","article-title":"Global birth prevalence of Orofacial clefts: A systematic review","volume":"98","author":"Panamonta V.","year":"2015","journal-title":"Journal of the Medical Association of Thailand"},{"key":"e_1_2_12_213_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1978.0107"},{"key":"e_1_2_12_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2012.03.006"},{"key":"e_1_2_12_215_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00704"},{"key":"e_1_2_12_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(72)90171-6"},{"key":"e_1_2_12_217_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1295-409"},{"key":"e_1_2_12_218_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-007-7166-z"},{"key":"e_1_2_12_219_1","doi-asserted-by":"publisher","DOI":"10.1038\/embor.2012.73"},{"key":"e_1_2_12_220_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.037051"},{"key":"e_1_2_12_221_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1006828"},{"key":"e_1_2_12_222_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp201"},{"key":"e_1_2_12_223_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1894"},{"key":"e_1_2_12_224_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI71946"},{"key":"e_1_2_12_225_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2006.08.006"},{"key":"e_1_2_12_226_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.002501"},{"key":"e_1_2_12_227_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1119"},{"key":"e_1_2_12_228_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1139740"},{"key":"e_1_2_12_229_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000054497.48394.D2"},{"key":"e_1_2_12_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.05.023"},{"key":"e_1_2_12_231_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2004.10.015"},{"key":"e_1_2_12_232_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.300"},{"key":"e_1_2_12_233_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2008.10.026"},{"key":"e_1_2_12_234_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.22546"},{"key":"e_1_2_12_235_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M108080200"},{"key":"e_1_2_12_236_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.69.040705.141236"},{"key":"e_1_2_12_237_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.050377"},{"key":"e_1_2_12_238_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22294"},{"key":"e_1_2_12_239_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.09.012"},{"issue":"3","key":"e_1_2_12_240_1","first-page":"227","article-title":"Cell release from the palatal shelves and the fusion line","volume":"11","author":"Schupbach P. M.","year":"1983","journal-title":"Journal de Biologie Buccale"},{"key":"e_1_2_12_241_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/8.10.1853"},{"key":"e_1_2_12_242_1","doi-asserted-by":"publisher","DOI":"10.1001\/archfaci.5.1.16"},{"key":"e_1_2_12_243_1","first-page":"1","article-title":"A cellular mechanism for the palatal shelf reorientation from a vertical to a horizontal plane in hamster: Light and electron microscopic study","volume":"53","author":"Shah R. M.","year":"1979","journal-title":"Journal of Embryology and Experimental Morphology"},{"key":"e_1_2_12_244_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-017-0362-2"},{"key":"e_1_2_12_245_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.07.018"},{"key":"e_1_2_12_246_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.10.017"},{"key":"e_1_2_12_247_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(92)90071-N"},{"key":"e_1_2_12_248_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1552"},{"key":"e_1_2_12_249_1","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1998_035_0065_cpfifb_2.3.co_2"},{"key":"e_1_2_12_250_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(97)00031-9"},{"key":"e_1_2_12_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(94)90170-8"},{"key":"e_1_2_12_252_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034517725707"},{"issue":"4","key":"e_1_2_12_253_1","first-page":"129","article-title":"Apoptosis and MMP\u20102, TIMP\u20102 expression in cleft lip and palate","volume":"15","author":"Smane L.","year":"2013","journal-title":"Stomatologija"},{"key":"e_1_2_12_254_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.037440"},{"key":"e_1_2_12_255_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2010.08.019"},{"key":"e_1_2_12_256_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1780"},{"key":"e_1_2_12_257_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng740"},{"key":"e_1_2_12_258_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420050107"},{"key":"e_1_2_12_259_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0854.2007.00611.x"},{"key":"e_1_2_12_260_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9946"},{"issue":"1","key":"e_1_2_12_261_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1242\/dev.125.1.95","article-title":"TGFbeta3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro","volume":"125","author":"Sun D.","year":"1998","journal-title":"Development"},{"key":"e_1_2_12_262_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1821064116"},{"key":"e_1_2_12_263_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201609037"},{"key":"e_1_2_12_264_1","doi-asserted-by":"publisher","DOI":"10.2535\/ofaj1936.78.5_179"},{"key":"e_1_2_12_265_1","doi-asserted-by":"publisher","DOI":"10.1038\/78119"},{"key":"e_1_2_12_266_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a018267"},{"key":"e_1_2_12_267_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.093948"},{"key":"e_1_2_12_268_1","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.041840tt"},{"key":"e_1_2_12_269_1","first-page":"563","article-title":"Facial and visceral arch development in the mouse embryo: A study by scanning electron microscopy","volume":"124","author":"Tamarin A.","year":"1977","journal-title":"Journal of Anatomy"},{"key":"e_1_2_12_270_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2010.03.015"},{"key":"e_1_2_12_271_1","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.58.191"},{"key":"e_1_2_12_272_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.11.001"},{"key":"e_1_2_12_273_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2010.12.004"},{"key":"e_1_2_12_274_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2012.06.017"},{"key":"e_1_2_12_275_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0807374105"},{"key":"e_1_2_12_276_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707057105"},{"key":"e_1_2_12_277_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33454"},{"key":"e_1_2_12_278_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420280112"},{"key":"e_1_2_12_279_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420010106"},{"key":"e_1_2_12_280_1","volume-title":"Intermediate filaments: A review","author":"Traub P.","year":"2012"},{"issue":"3","key":"e_1_2_12_281_1","first-page":"333","article-title":"TGF\u2010beta3 is required for the adhesion and intercalation of medial edge epithelial cells during palate fusion","volume":"46","author":"Tudela C.","year":"2002","journal-title":"The International Journal of Developmental Biology"},{"key":"e_1_2_12_282_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201004108"},{"key":"e_1_2_12_283_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(09)88004-6"},{"issue":"4","key":"e_1_2_12_284_1","first-page":"359","article-title":"Short rib\u2010polydactyly syndrome: A case report","volume":"45","author":"Turkmen M.","year":"2003","journal-title":"The Turkish Journal of Pediatrics"},{"key":"e_1_2_12_285_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv228"},{"issue":"3","key":"e_1_2_12_286_1","first-page":"216","article-title":"Incidence of cleft lip, cleft palate, and cleft lip and palate among races: A review","volume":"24","author":"Vanderas A. P.","year":"1987","journal-title":"The Cleft Palate Journal"},{"key":"e_1_2_12_287_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.15.8551"},{"key":"e_1_2_12_288_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2005.07.027"},{"key":"e_1_2_12_289_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(03)00240-9"},{"key":"e_1_2_12_290_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.95"},{"key":"e_1_2_12_291_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13630-016-0030-8"},{"key":"e_1_2_12_292_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar4362"},{"issue":"3","key":"e_1_2_12_293_1","first-page":"99","article-title":"Deficient and delayed primary palatal fusion and mesenchymal bridge formation in cleft lip\u2010liable strains of mice","volume":"15","author":"Wang K. Y.","year":"1995","journal-title":"Journal of Craniofacial Genetics and Developmental Biology"},{"key":"e_1_2_12_294_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.040279"},{"key":"e_1_2_12_295_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091760311"},{"key":"e_1_2_12_296_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2009.01588.x"},{"key":"e_1_2_12_297_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.23.7.2264-2276.2003"},{"key":"e_1_2_12_298_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2018.00008"},{"key":"e_1_2_12_299_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep17735"},{"key":"e_1_2_12_300_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S139639"},{"key":"e_1_2_12_301_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7290318"},{"key":"e_1_2_12_302_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21280"},{"key":"e_1_2_12_303_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2008.06.004"},{"key":"e_1_2_12_304_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M313526200"},{"key":"e_1_2_12_305_1","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2660"},{"key":"e_1_2_12_306_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.09.034"},{"key":"e_1_2_12_307_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209712"},{"key":"e_1_2_12_308_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402060302"},{"key":"e_1_2_12_309_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.19.11423"},{"key":"e_1_2_12_310_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2443.2012.01601.x"},{"key":"e_1_2_12_311_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02013"},{"key":"e_1_2_12_312_1","doi-asserted-by":"publisher","DOI":"10.3181\/0812-MR-365"},{"key":"e_1_2_12_313_1","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1055\/s-0039-1699375","article-title":"Cleft lip and palate genetics and application in early embryological development","volume":"42","author":"Yu W.","year":"2009","journal-title":"Indian Journal of Plastic Surgery"},{"key":"e_1_2_12_314_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvg.20728"},{"key":"e_1_2_12_315_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv333"},{"key":"e_1_2_12_316_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.17.4135"}],"container-title":["Birth Defects Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdr2.1768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.1768","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bdr2.1768","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.1768","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T09:14:21Z","timestamp":1693818861000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdr2.1768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,29]]},"references-count":315,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1002\/bdr2.1768"],"URL":"https:\/\/doi.org\/10.1002\/bdr2.1768","archive":["Portico"],"relation":{},"ISSN":["2472-1727","2472-1727"],"issn-type":[{"value":"2472-1727","type":"print"},{"value":"2472-1727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,29]]},"assertion":[{"value":"2020-03-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}