{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T06:58:07Z","timestamp":1779173887027,"version":"3.51.4"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T00:00:00Z","timestamp":1664755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Congenital cytomegalovirus (cCMV) is not a nationally notifiable condition, and little is known about how U.S. health departments (HDs) currently conduct cCMV surveillance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We surveyed U.S. HDs that conduct cCMV surveillance or screening activities identified through a web\u2010based assessment. Meetings were held with each HD to enhance our understanding of survey responses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten states are systematically collecting cCMV case data to track cCMV cases during early infancy and to provide resources and services to families. Cases are ascertained using cCMV diagnostic codes, reported diagnosis, or laboratory results. Data elements collected for each case include demographics (all 10 states), clinical signs (8 states), laboratory data (4 states), treatment (4 states), and long\u2010term outcomes (1 state). Annual number of cases reported by HDs ranged from 3 to 47 cases\/year in seven states, which was much lower than the expected number of cCMV cases. All 10 HDs have the ability to analyze data collected and four disseminate findings. Major challenges of surveillance reported by HDs were lack of standardized case definitions, personnel constraints, and limited funding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A comprehensive account of cCMV disease burden is severely limited by low case ascertainment and paucity of data on long\u2010term outcomes. A standardized public health case definition for cCMV would improve consistency in measuring disease prevalence across jurisdictions and over time. Surveillance for cCMV has the potential to increase disease awareness and inform strategies to prevent cCMV\u2010associated disabilities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2098","type":"journal-article","created":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T06:40:24Z","timestamp":1664865624000},"page":"11-20","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Congenital cytomegalovirus surveillance in the United States"],"prefix":"10.1002","volume":"115","author":[{"given":"Kelley","family":"Raines","sequence":"first","affiliation":[{"name":"ASRT, Inc., Contracting agency to the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristen Nichols","family":"Heitman","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Leung","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate R.","family":"Woodworth","sequence":"additional","affiliation":[{"name":"Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Van T.","family":"Tong","sequence":"additional","affiliation":[{"name":"Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Sugerman","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana M.","family":"Lanzieri","sequence":"additional","affiliation":[{"name":"Division of Viral Diseases, National Center for Immunization and Respiratory Diseases Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,10,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2018.09.017"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2021.2006536"},{"key":"e_1_2_9_4_1","unstructured":"Department of Pediatrics(2021).Congenital CMV Disease Research Clinic & Registry. Baylor College of Medicine.https:\/\/www.bcm.edu\/departments\/pediatrics\/divisions\u2010and\u2010centers\/congenital\u2010cmv\u2010disease\u2010research\u2010clinic\u2010registry"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2020.5441"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.544"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-053655"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.04.043"},{"key":"e_1_2_9_9_1","first-page":"1","article-title":"Updated guidelines for evaluating public health surveillance systems recommendations from the guidelines working group. MMWR. Recommendations and reports: Morbidity and mortality weekly report","volume":"50","author":"German R. R.","year":"2001","journal-title":"Recommendations and Reports\/Centers for Disease Control"},{"key":"e_1_2_9_10_1","unstructured":"Gosdin L. K. Wallace B. Lanzieri T. M. Olsen E. O. Lewis E. L. Chang D. J. \u2026Woodworth K.(in press).Six\u2010month outcomes of infants born to people with SARS\u2010CoV\u20102 in pregnancy 10 U.S. jurisdictions.Pediatrics."},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2021.1890556"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.3.665"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/17843286.2019.1683262"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268815002708"},{"key":"e_1_2_9_15_1","volume-title":"Tracking clinical outcomes of infants identified with cytomegalovirus infection in neonatal intensive care units\u2013California, 2010\u20132021","author":"Lanzieri T. M.","year":"2022"},{"key":"e_1_2_9_16_1","unstructured":"Minnesota Department of Public Health(2022).Congenital cytomegalovirus approved for addition to newborn screening panel [Press release].https:\/\/www.health.state.mn.us\/news\/pressrel\/2022\/newborn020222.html."},{"key":"e_1_2_9_17_1","unstructured":"National Center for Health Statistics(2022).Data are from the Natality Records 2016\u20132020 as compiled from data provided by the 57 vital statistics jurisdictions through the Vital Statistics Cooperative Program. In National Vital Statistics System Natality on CDC WONDER Online Database.: Centers for Disease Control and Prevention."},{"key":"e_1_2_9_18_1","unstructured":"National Center on Birth Defects and Developmental Disabilities(2022).Surveillance for Emerging Threats to Mothers and Babies Network. Centers for Disease Control and Prevention.https:\/\/www.cdc.gov\/ncbddd\/set-net\/index.html"},{"key":"e_1_2_9_19_1","unstructured":"Newborn Screening Ontario(2022).Hearing Loss Risk Factor Screening. Children's Hospital of Eastern Ontario.https:\/\/www.newbornscreening.on.ca\/en\/page\/overview"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12883"},{"key":"e_1_2_9_21_1","volume-title":"Case\u2010finding and validation of congenital cytomegalovirus (cCMV) related hospital admissions in Michigan infants under one year of age","author":"Quarshie E.","year":"2016"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(17)30143-3"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2019.104231"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijns4020016"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2010.199901"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1683958"},{"issue":"1","key":"e_1_2_9_27_1","first-page":"e1","article-title":"Congenital cytomegalovirus infection in Canada: Active surveillance for cases diagnosed by paediatricians","volume":"19","author":"Vaudry W.","year":"2014","journal-title":"Paediatrics & Child Health"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000003532"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-020-03106-y"}],"container-title":["Birth Defects Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.2098","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/bdr2.2098","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.2098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T11:16:07Z","timestamp":1692443767000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdr2.2098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,3]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1002\/bdr2.2098"],"URL":"https:\/\/doi.org\/10.1002\/bdr2.2098","archive":["Portico"],"relation":{},"ISSN":["2472-1727","2472-1727"],"issn-type":[{"value":"2472-1727","type":"print"},{"value":"2472-1727","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,3]]},"assertion":[{"value":"2022-07-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}