{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T04:10:01Z","timestamp":1775794201335,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009698","name":"Hawassa University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009698","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Neural tube closure defect (NTD) such as spinal bifida and anencephaly are serious neurological disabilities that occur when the neural tube does not close completely within 28\u2009days of conception. Even though Folic acid supplementation during and before pregnancy is proved to significantly reduces the risk of NTDs. Currently only 23% of folic acid preventable NTD achieved\u00a0Worldwide; mainly due to lack of awareness about folic acid supplementation. This study was aimed to assess the knowledge of Folic acid supplementation among pregnant women attending antenatal care at public health facilities in Hawassa Ethiopia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Institution based cross\u2010sectional study was employed among 358 pregnant women attending antenatal care. Data were collected using an interviewer\u2010administered structured questionnaire and analyzed using SPSS version 22. The knowledge of Folic acid supplementation was assessed using six multiple\u2010choice questions. The association between the dependent and independent variables were analyzed using Binary Logistic regression model and statistically significant predictors at <jats:italic>p<\/jats:italic>\u2010value &lt;.05 at 95% CI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study indicated that only 7.5% (95% CI, 5.3\u201310.1) of pregnant women had good knowledge of Folic acid supplementation. The pregnant women who had a history of at least one previous pregnancy loss AOR\u00a0=\u00a012.64 (95% CI: 4.98, 32.08) and those who had preconception consultation AOR = 11.77 (95% CI: 3.01, 46.07) were more likely to have good knowledge of periconceptional folic acid supplementation as compared to their counterpart.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The knowledge of periconceptional folic acid supplementation among pregnant women was worryingly low in the study area. Alternative and more effective strategies are needed if the population of Ethiopia is to benefit fully from the folic acid prevention of NTDs. Thus, in Ethiopia the future strategies should focus on the possible way to reach the last group through fortification of staple foods with folic acid along with improving women's awareness on folic acid importance in reducing Neural tube defects.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2157","type":"journal-article","created":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T12:14:26Z","timestamp":1676463266000},"page":"647-657","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Knowledge of periconceptional folic acid supplementation and associated factors among pregnant women attending antenatal care at public health facilities in Hawassa, South Ethiopia"],"prefix":"10.1002","volume":"115","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0338-1470","authenticated-orcid":false,"given":"Merga","family":"Besho","sequence":"first","affiliation":[{"name":"Department of Midwifery, School of Nursing and Midwifery Wollega University  Nekemte Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andargachew","family":"Kassa","sequence":"additional","affiliation":[{"name":"Departments of Midwifery, College of Medicine and Health Science Hawassa University  Hawassa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dubale","family":"Dula","sequence":"additional","affiliation":[{"name":"Departments of Midwifery, College of Medicine and Health Science Hawassa University  Hawassa Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Getahun","family":"Fetensa","sequence":"additional","affiliation":[{"name":"Departments of Nursing, School of Nursing and Midwifery Wollega University  Nekemte Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadesse","family":"Tolossa","sequence":"additional","affiliation":[{"name":"Deakin Health Economics, School of Health and Social Development, Institute for Health Transformation Deakin university  Geelong Victoria Australia"},{"name":"Department of Public Health, Institute of Health Science Wollega University  Nekemte, Oromia, Ethiopia Nekemte Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bizuneh","family":"Wakuma","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics, Institute of Health Sciences Wollega University  Nekemte Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misganu Teshoma","family":"Regasa","sequence":"additional","affiliation":[{"name":"Department of Midwifery, School of Nursing and Midwifery Wollega University  Nekemte Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,15]]},"reference":[{"issue":"9","key":"e_1_2_11_2_1","first-page":"7","article-title":"Knowledge, attitude and practice regarding folic acid among pregnant women in Benghazi, Libya","volume":"20","author":"Abdulmalek L. 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