{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:33:20Z","timestamp":1747146800645,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Classic bladder exstrophy (CBE) is a rare anterior midline birth defect that remains a challenge for pediatric surgeons. Despite multiple reconstructive methods, outcomes vary widely in various reports. This study aims to compare the success rate and complications of modern staged repair of exstrophy (MSRE) in each gender and compare together.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cross\u2010sectional study included cases of CBE between 2010 and 2020 that underwent MSRE. Short\u2010term follow\u2010up results, including incontinence rate, vesicoureteral reflux (VUR), urinary infections, deformed genitalia, and so on, were measured in each gender, and their differences were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 40 newborns with CBE who underwent MSRE, 25 (62.5%) were boys, while the others had non\u2010male genitalia. The rates of incontinence, VUR, dehiscence, and fistulas did not differ significantly between genders. However, chronic urinary tract infections (UTIs) were more frequent in girls, and boys were more likely to have malformed genitalia (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings indicate a similar rate of complications in each gender. However, chronic UTIs and external genitalia deformities were significantly more common in girls and boys, respectively. Further large\u2010sized controlled trials may be needed to corroborate these findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2228","type":"journal-article","created":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T04:33:15Z","timestamp":1690605195000},"page":"1469-1474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The outcome and complications of modern staged repair surgery in newborns with classic bladder exstrophy in different genders: A retrospective study"],"prefix":"10.1002","volume":"115","author":[{"given":"Amin Haj","family":"Esmaeilizadeh","sequence":"first","affiliation":[{"name":"Pediatric Surgery Research Center, Research Institute for Children's Health Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gholamreza","family":"Ebrahimisaraj","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Research Center, Research Institute for Children's Health Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Sarafi","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Research Center, Research Institute for Children's Health Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohsen","family":"Rouzrokh","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Research Center, Research Institute for Children's Health Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leily","family":"Mohajerzadeh","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Research Center, Research Institute for Children's Health Shahid Beheshti University of Medical Sciences  Tehran 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