{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:03:58Z","timestamp":1753862638600,"version":"3.41.2"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T00:00:00Z","timestamp":1706659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Surveillance of birth defects is critical to track prevalence and inform prevention efforts. Previous studies suggest that restricting abortion may lead to an increase in birth defect prevalence. However, it is unclear how abortion legislation will impact birth defect prevalence estimates reported by state\u2010based surveillance programs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We described current abortion legislation and surveillance program methodology, by state, as a foundation for understanding the program\u2010level impact on surveillance. We estimated the quantitative effect of abortion legislation on birth defect prevalence for various scenarios using first\u2010order Monte Carlo simulation. Finally, we discuss the implications for interpreting birth defect prevalence estimates following abortion legislation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among states that restrict abortion \u226418\u2009weeks and have a surveillance program (<jats:italic>N<\/jats:italic>\u2009=\u200919), eight programs (42%) capture elective terminations (&lt;20\u2009weeks) and 17 (89%) include fetal deaths (\u226520\u2009weeks) in their estimates. Abortion bans increased the prevalence of any birth defect by 16.6%, 15.8%, and 8.7% for systems with live births only, all outcomes \u226520\u2010weeks, and all outcomes \u226510\u2010weeks, respectively. We found the largest change in prevalence for anencephaly with an estimated 32.5% increase among systems with live births only.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Abortion legislation is likely to further exacerbate the difficulties of multi\u2010state birth defect research and surveillance, while also hindering analysis of intra\u2010state prevalence trends. Birth defect surveillance systems in states with abortion bans may wish to consider monitoring and reporting changes in pregnancy outcomes and infant survival, in addition to birth defect prevalence, to inform public health and health care service needs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2302","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T06:50:12Z","timestamp":1706770212000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Implications of abortion legislation on birth defect surveillance"],"prefix":"10.1002","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3316-2797","authenticated-orcid":false,"given":"Amanda L.","family":"Elmore","sequence":"first","affiliation":[{"name":"Birth Defect Surveillance Program College of Public Health, University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9217-3723","authenticated-orcid":false,"given":"Dominique","family":"Heinke","sequence":"additional","affiliation":[{"name":"Center for Birth Defects Research and Prevention Bureau of Family Health and Nutrition, Massahusetts Department of Public Health  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Paul","family":"Tanner","sequence":"additional","affiliation":[{"name":"Birth Defect Surveillance Program College of Public Health, University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3489-401X","authenticated-orcid":false,"given":"Russell S.","family":"Kirby","sequence":"additional","affiliation":[{"name":"Birth Defect Surveillance Program College of Public Health, University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah G.","family":"Obican","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Morsani College of Medicine University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0077-6023","authenticated-orcid":false,"given":"Jason L.","family":"Salemi","sequence":"additional","affiliation":[{"name":"Birth Defect Surveillance Program College of Public Health, University of South Florida  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,31]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2005.00666.x"},{"key":"e_1_2_5_3_1","unstructured":"Centers for Disease Control and Prevention. (n.d).Fetal Deaths 2014\u20132021 expanded request. National Vital Statistics System Fetal Deaths Records 2014\u20132021 on CDC WONDER Online Database. Accessed on 1\/4\/2024 from Fetal Deaths 2014\u20132021 expanded Request Form (cdc.gov)."},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.3684"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.15620\/cdc:120700"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.90008"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5148"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2023.101441"},{"key":"e_1_2_5_9_1","unstructured":"Guttmacher Institute. (2023).State bans on abortion throughout pregnancy. Retrieved May 31 2023 fromhttps:\/\/www.guttmacher.org\/state\u2010policy\/explore\/state\u2010policies\u2010later\u2010abortions"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-022-04770-4"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23086"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.ss7110a1"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/gco.0000000000000915"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.287.12.1561"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20779"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdr2.1589"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/phh.0000000000000221"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/tog.12028"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000005291"},{"key":"e_1_2_5_20_1","unstructured":"National Birth Defects Prevention Network. (2023).Birth defects data tables and directory. Retrieved May 31 2023."},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.2910"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0000000000000583"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000005094"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/ppe.12417"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4306"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7227a1"},{"key":"e_1_2_5_27_1","unstructured":"United States Supreme Court. (2022).Dobbs State Health Officer of the Mississippi Department of Health et al. v. Jackson Women's Health Organization et al."}],"container-title":["Birth Defects Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.2302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T05:37:40Z","timestamp":1709185060000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdr2.2302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,31]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1002\/bdr2.2302"],"URL":"https:\/\/doi.org\/10.1002\/bdr2.2302","archive":["Portico"],"relation":{},"ISSN":["2472-1727","2472-1727"],"issn-type":[{"type":"print","value":"2472-1727"},{"type":"electronic","value":"2472-1727"}],"subject":[],"published":{"date-parts":[[2024,1,31]]},"assertion":[{"value":"2023-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2302"}}