{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T10:03:46Z","timestamp":1781172226153,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T00:00:00Z","timestamp":1708041600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The condition of monozygotic, monochorionic triplet fetuses with a pair of conjoined twins is extremely rare (close to one in a million births), presents challenges in its management, and with poor prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>We report a case of monochorionic diamniotic triplet pregnancy, ultrasound at 14\u2009weeks shows a pair of conjoined thoracopagus fetuses, sharing heart, liver, and umbilical cord, in addition to omphalocele. The third fetus, without malformations, presents signs of early heart failure compatible with twin\u2010to\u2010twin transfusion syndrome. It was decided to carry out expectant management where at 18\u2009weeks, intrauterine death of the three fetuses occurs. An abortion is performed by hysterotomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The treatment in these cases is discussed, three management options have been proposed: expectant management, selective reduction of the conjoined fetuses, or termination of the pregnancy. A review of the literature found only 12 cases with this combination of pathologies, in which only 3 normal fetuses (25%) survived and none of the conjoined twins survived. To our knowledge, this case is the first of a monochorionic triplet pregnancy with conjoined fetuses complicated with early twin\u2010to\u2010twin transfusion.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2317","type":"journal-article","created":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T08:49:54Z","timestamp":1708073394000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Monochorionic triplet pregnancy complicated by conjoined twins and early twin\u2013twin transfusion syndrome"],"prefix":"10.1002","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9083-9771","authenticated-orcid":false,"given":"Juan Carlos","family":"Bustos","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, San Juan de Dios Hospital University of Chile  Chile"},{"name":"Maternal\u2010Fetal Medicine Unit, San Juan de Dios Hospital  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3199-9932","authenticated-orcid":false,"given":"Helga","family":"Vera","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, San Juan de Dios Hospital University of Chile  Chile"},{"name":"Maternal\u2010Fetal Medicine Unit, San Juan de Dios Hospital  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paz","family":"Ahumada","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, San Juan de Dios Hospital University of Chile  Chile"},{"name":"Maternal\u2010Fetal Medicine Unit, San Juan de Dios Hospital  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Martin","sequence":"additional","affiliation":[{"name":"Maternal\u2010Fetal Medicine Unit, San Juan de Dios Hospital  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004397"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.23387"},{"issue":"6","key":"e_1_2_6_4_1","first-page":"459","article-title":"Triplet pregnancy complicated by intrauterine fetal death of conjoined twins from an umbilical cord accident of an acardius. 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