{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:03:35Z","timestamp":1792224215493,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:00:00Z","timestamp":1733616000000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","award":["U38OT000199"],"award-info":[{"award-number":["U38OT000199"]}],"id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are limited studies on educational outcomes of children born with esophageal atresia (EA) with or without tracheoesophageal fistula (TEF). We aimed to compare 3rd to 5th grade academic proficiency among children born with EA\/TEF versus unaffected children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Children born with EA\/TEF (2000\u20132005) were identified from the Arkansas Reproductive Health Monitoring System. For each child born with EA\/TEF, up to two unaffected children were selected from birth certificates and matched on hospital and month of birth, sex, and race and ethnicity. Data on NICU hospitalization were abstracted from medical records at Arkansas' only pediatric specialty hospital. The study outcomes were 3rd to 5th grade proficiency on literacy and mathematic standardized achievement tests, referral to special education, and days of school absence. Regression models were used to assess the association of outcome measures with diagnosis of EA\/TEF, after adjusting for differences in covariates between EA\/TEF and unaffected children and accounting for paired correlations using the generalized estimating equation method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final cohort included 20 surviving children born with EA\/TEF and 31 unaffected children. There was no significant difference in literacy (3rd: 70% vs. 71%; 4th: 83% vs. 81%; 5th: 94% vs. 87%, p\u2009&gt;\u20090.05) or mathematics proficiency (3rd: 80% vs. 87%; 4th: 83% vs. 78%; 5th: 75% vs. 78%, <jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05), referral to special education (20% vs. 19%, <jats:italic>p<\/jats:italic>\u2009=\u20090.65), or total days of school absence (47 vs. 26\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.07) between EA\/TEF and unaffected children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Children born with EA\/TEF had comparable academic proficiency to unaffected children.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2417","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T07:21:33Z","timestamp":1733728893000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Childhood Educational Outcomes of Infants Born With Esophageal Atresia With or Without Tracheoesophageal Fistula"],"prefix":"10.1002","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0868-8420","authenticated-orcid":false,"given":"Nahed O.","family":"ElHassan","sequence":"first","affiliation":[{"name":"Department of Pediatrics (Neonatal\u2010Perinatal Medicine), Arkansas Children's Hospital University of Arkansas for Medical Sciences  Little Rock Arkansas USA"},{"name":"Arkansas Center for Birth Defects Research and Prevention  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2668-4901","authenticated-orcid":false,"given":"Ruiqi","family":"Cen","sequence":"additional","affiliation":[{"name":"Arkansas Center for Birth Defects Research and Prevention  Little Rock Arkansas USA"},{"name":"Department of Epidemiology, Fay W. Boozman College of Public Heath University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4364-7165","authenticated-orcid":false,"given":"Charles P.","family":"Pugh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics (Neonatal\u2010Perinatal Medicine), Arkansas Children's Hospital University of Arkansas for Medical Sciences  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2579-7146","authenticated-orcid":false,"given":"Chary","family":"Akmyradov","sequence":"additional","affiliation":[{"name":"Arkansas Children's Research Institute  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Ying","sequence":"additional","affiliation":[{"name":"Arkansas Center for Birth Defects Research and Prevention  Little Rock Arkansas USA"},{"name":"Department of Biostatistics, Fay W. Boozman College of Public Heath University of Arkansas for Medical Sciences  Little Rock Arkansas USA"},{"name":"Department of Family Medicine, School of Medicine University of Colorado Anschutz Medical Campus, Aurora CO  USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8369-2326","authenticated-orcid":false,"given":"Anthony","family":"Goudie","sequence":"additional","affiliation":[{"name":"Arkansas Center for Birth Defects Research and Prevention  Little Rock Arkansas USA"},{"name":"Department of Health Policy and Management, Fay W. 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