{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T08:04:40Z","timestamp":1753862680237,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,27]],"date-time":"2025-02-27T00:00:00Z","timestamp":1740614400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to develop an esophageal atresia (EA) model using fresh sheep esophagus, trachea, and lungs to simulate a realistic thoracoscopic surgical environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A thoracoscopic trainer box was used with fresh sheep tissues (esophagus, trachea, and lungs) to create an EA and tracheoesophageal fistula (TEF) model. The distal esophagus was anastomosed to the trachea, and a bicycle pump was integrated to simulate lung function. Additional components, such as a simulated azygos vein and parietal pleura, enhanced the model's realism for surgical training.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The developed EA\u2010TEF model was created in six steps, including pleural dissection, azygos vein control, TEF division, and esophageal anastomosis. The procedure used a thoracoscopic trainer box, sheep tissues, and standard instruments. A bicycle pump simulated lung function, and careful techniques were employed for vein ligation and esophageal anastomosis. After the posterior wall was sutured, an 8\u2009Fr feeding tube was inserted. The total cost of the model was $260, with reusable equipment and a $10 recurring cost for sheep tissues.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study successfully developed a cost\u2010effective and anatomically accurate thoracoscopic model for EA and TEF repair using fresh sheep tissue.<\/jats:p><\/jats:sec>","DOI":"10.1002\/bdr2.2458","type":"journal-article","created":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T02:41:38Z","timestamp":1741488098000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Development of a Thoracoscopic Model for Birth Defect Esophageal Atresia and Tracheoesophageal Fistula Using Fresh Sheep Tissues"],"prefix":"10.1002","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3563-1230","authenticated-orcid":false,"given":"Mustafa","family":"Azizoglu","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Istanbul Esenyurt Necmi Kadioglu State Hospital  Istanbul Turkey"},{"name":"Department of Stem Cell and Tissue Engineering &amp; 3D Bioprinting Istinye University  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6720-1515","authenticated-orcid":false,"given":"Mehmet Hanifi","family":"Okur","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Dicle University  Diyarbak\u0131r Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010024\u201005827\u20105"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.161690"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.09.069"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464\u2010024\u201011063\u20108"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.03.023"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13304\u2010023\u201001684\u20104"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2016.0214"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010024\u201005724\u2010x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383\u2010021\u201004913\u20102"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2014.04.016"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2016.04.018"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/ases.12411"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12237251"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010012\u20101651\u20108"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.08.002"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2024.06.023"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201062154\u20104"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1286946"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000889"}],"container-title":["Birth Defects Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdr2.2458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T10:47:22Z","timestamp":1745232442000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdr2.2458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,27]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/bdr2.2458"],"URL":"https:\/\/doi.org\/10.1002\/bdr2.2458","archive":["Portico"],"relation":{},"ISSN":["2472-1727","2472-1727"],"issn-type":[{"type":"print","value":"2472-1727"},{"type":"electronic","value":"2472-1727"}],"subject":[],"published":{"date-parts":[[2025,2,27]]},"assertion":[{"value":"2024-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e2458"}}