{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:07:55Z","timestamp":1790255275680,"version":"4.1.0"},"reference-count":71,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Congenital anomalies (CA) are health problems that can significantly affect individuals, families, health systems, and society. Our aim is to present the characteristics of CA observed in babies born at our institution between 2014 and 2023, including the Covid\u201019 pandemic period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Retrospective data obtained from the delivery room records and hospital information system of Pamukkale University Hospital were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the 10\u2010year period covered by our study at our institution, 16,030 births occurred, and 941 (5.87%) newborns were diagnosed with CA. The most common anomalies were cardiovascular system (CVS) (42%), other congenital malformations (5%), musculoskeletal system (4%), and central nervous system (CNS) anomalies (7%). Two hundred twenty\u2010nine newborns (24%) were found to have multiple congenital anomalies. The prevalence of CA was higher in 2020, 2021, and 2022 (during the COVID\u201019 pandemic) compared to other years. The mortality rate among newborns with CA was 21.25%. Of the CA babies who died, 37.5% had CVS, 30% had multiple anomalies, and 9% had CNS anomalies. The mortality rate due to congenital anomalies, based on the total number of births in our hospital, was 1.25%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We found that the mortality rate among newborns with CA was 21.25% and that the incidence of anomalies increased during the COVID\u201019 pandemic. Multidisciplinary efforts are required to provide parents with the necessary information during pregnancy and the prepregnancy planning period. It is crucial to examine the prevalence of CA during the Covid\u201019 pandemic period in other regional studies and to evaluate the impact of such epidemics on anomalies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/bdr2.70113","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T03:21:55Z","timestamp":1788319315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Congenital Anomaly Prevalence: A 10\u2010Year Retrospective Study in a Tertiary Hospital in Turkey"],"prefix":"10.1002","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8731-0631","authenticated-orcid":false,"given":"H\u00fclya","family":"\u00c7etin","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Histology and Embryology Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1552-8824","authenticated-orcid":false,"given":"Serhan","family":"Sorkun","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Ophtalmology Kocaeli University  Kocaeli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2135-6418","authenticated-orcid":false,"given":"\u0130lknur","family":"Lafc\u0131","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Histology and Embryology Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8003-9586","authenticated-orcid":false,"given":"Derya","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Obstetrics and Gynocology Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bab\u00fcr","family":"Kaleli","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Obstetrics and Gynocology Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zmert Muhammet Ali","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pediatrics Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2136-8192","authenticated-orcid":false,"given":"Bilgin K\u0131ray","family":"Vural","sequence":"additional","affiliation":[{"name":"Denizli Health Services Vocational School, Department of Medical Services and Techniques Pamukkale University  Denizli T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884\u2010018\u20102141\u20102"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/121.2.192"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6602a1"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdr2.1645"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23507"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20658"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild\u20102014\u2010307347"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747\u20100803.2007.00105.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3475"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00145656"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.07.006"},{"key":"e_1_2_10_13_1","volume-title":"March of Dimes Global Report on Birth Defects: The Hidden Toll of Dying and Disabled Children","author":"Christianson A.","year":"2006"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1159\/000509117"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1995.03530210052030"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404\u2010024\u201007599\u20108"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.728"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u201090\u2010481\u20109485\u20108_20"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000437597.44550.5d"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000219172.16638.f9"},{"issue":"5","key":"e_1_2_10_21_1","article-title":"Infant Mortality in the United States, 2022: Data From the Period Linked Birth\/Infant Death File","author":"Ely D. 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