{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:08:01Z","timestamp":1760954881362},"reference-count":19,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,8,24]],"date-time":"2006-08-24T00:00:00Z","timestamp":1156377600000},"content-version":"vor","delay-in-days":84,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2006,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>BACKGROUND:<\/jats:bold> Little is known about the association between maternal nativity and congenital malformations among Hispanics living in the United States. <jats:bold>METHODS:<\/jats:bold> We conducted a cross\u2010sectional study to investigate the association between maternal nativity and various congenital malformations among singleton live\u2010births born to Hispanic women in New York from 1993 to 2001. Birth certificates, used to identify maternal birthplace, were linked with congenital malformation registry files to obtain birth defects outcome. We examined how the risk of birth defects varied by maternal birthplace by estimating the adjusted odds ratios (aORs) using logistic regression. <jats:bold>RESULTS:<\/jats:bold> A foreign maternal birth showed statistically negative associations with overall congenital malformations (aOR, 0.70; 95% CI, 0.68\u20130.73), cardiovascular defects (aOR, 0.85; 95% CI, 0.77\u20130.93), central nervous system defects (aOR, 0.76; 95% CI, 0.63\u20130.91), and multiple defects (aOR, 0.80; 95% CI, 0.74\u20130.86). Specifically, foreign\u2010born Hispanic women were statistically at reduced risk to deliver live babies with cleft palate (aOR, 0.56; 95% CI, 0.40\u20130.80), atresia and stenosis of rectum or anus (aOR, 0.58; 95% CI, 0.35\u20130.97), and craniosynostosis (aOR, 0.71; 95% CI, 0.51\u20130.99). Hispanic mothers born in Puerto Rico had a similar risk of delivering children with birth defects compared to U.S.\u2010born Hispanic mothers. In contrast, Hispanic mothers born in Mexico, or Cuba and Central and South America were at reduced risk of delivering infants with overall congenital malformations (aOR, 0.64; 95% CI, 0.60\u20130.67) and (aOR, 0.65; 95% CI, 0.63\u20130.68), respectively. <jats:bold>CONCLUSIONS:<\/jats:bold> Foreign\u2010born Hispanic mothers had a slightly lower risk to deliver live\u2010born singleton infants with major congenital malformations than did U.S. born Hispanic mothers. Birth Defects Research (Part A) 76:467\u2013473, 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bdra.20270","type":"journal-article","created":{"date-parts":[[2006,8,24]],"date-time":"2006-08-24T19:19:36Z","timestamp":1156447176000},"page":"467-473","source":"Crossref","is-referenced-by-count":15,"title":["Maternal birthplace and major congenital malformations among New York Hispanics"],"prefix":"10.1002","volume":"76","author":[{"given":"Motao","family":"Zhu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte","family":"Druschel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,8,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1001\/jama.1991.03460020071031","article-title":"Infant mortality among Hispanics: a portrait of heterogeneity","volume":"265","author":"Becerra J","year":"1991","journal-title":"JAMA"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20012"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116980"},{"key":"e_1_2_6_5_1","first-page":"17","article-title":"Ethnicity, acculturation and obstetric outcomes, different risk factor profile in low\u2010 and high\u2010acculturation Hispanics and in White Non\u2010Hispanics","volume":"49","author":"Coonrod DV","year":"2004","journal-title":"J Reprod Med"},{"key":"e_1_2_6_6_1","first-page":"229","article-title":"Pregnancy outcomes and risk factors in Mexican Americans: the effects of language use and mother's birthplace","volume":"7","author":"English PB","year":"1997","journal-title":"Ethn Dis"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.80.Suppl.61"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.89.8.1238"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(02)90327-5"},{"key":"e_1_2_6_10_1","first-page":"1","article-title":"The emerging Hispanic population: a foundation for cancer prevention and control","volume":"18","author":"Ramirez AG","year":"1995","journal-title":"Monogr Natl Cancer Inst"},{"key":"e_1_2_6_11_1","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1542\/peds.96.5.880","article-title":"Impact of prenatal diagnosis on the birth prevalence of neural tube defects, Atlanta, 1990\u20131991","volume":"96","author":"Roberts HE","year":"1995","journal-title":"Pediatrics"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.79.9.1263"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3549(04)50051-1"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.87.9.1467"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.86.6.837"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1983.tb13823.x"},{"key":"e_1_2_6_17_1","first-page":"4","volume-title":"Census 2000 brief: coming from the Americas: a profile of the nation's Latin American foreign born","author":"U.S. Census Bureau","year":"2000"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a008953"},{"key":"e_1_2_6_19_1","first-page":"647","article-title":"Childbearing characteristics of US\u2010born and foreign\u2010born Hispanic mothers","volume":"100","author":"Ventura SJ","year":"1985","journal-title":"Public Health Rep"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20208"}],"container-title":["Birth Defects Research Part A: Clinical and Molecular Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdra.20270","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdra.20270","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T02:34:16Z","timestamp":1697510056000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdra.20270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1002\/bdra.20270"],"URL":"https:\/\/doi.org\/10.1002\/bdra.20270","archive":["Portico"],"relation":{},"ISSN":["1542-0752","1542-0760"],"issn-type":[{"value":"1542-0752","type":"print"},{"value":"1542-0760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6]]}}}