{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:42:38Z","timestamp":1780465358592,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3530,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defect Res A"],"published-print":{"date-parts":[[2006,10]]},"DOI":"10.1002\/bdra.20307","type":"journal-article","created":{"date-parts":[[2006,10,6]],"date-time":"2006-10-06T22:58:53Z","timestamp":1160175533000},"page":"693-705","source":"Crossref","is-referenced-by-count":84,"title":["Trends of selected malformations in relation to folic acid recommendations and fortification: An international assessment"],"prefix":"10.1002","volume":"76","author":[{"given":"Lorenzo D.","family":"Botto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Lisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Bower","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Canfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirupa","family":"Dattani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"De Vigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermien","family":"De Walle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Erickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane","family":"Halliday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorentz M.","family":"Irgens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Brian","family":"Lowry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"McDonnell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Metneki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Poetzsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annukka","family":"Ritvanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Robert-Gnansia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Siffel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Stoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo","family":"Mastroiacovo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006]]},"reference":[{"key":"10.1002\/bdra.20307-BIB1","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1056\/NEJM199911113412001","volume":"341","author":"Berry","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1002\/bdra.20307-BIB2","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1056\/NEJM199911113412006","volume":"341","author":"Botto","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1002\/bdra.20307-BIB3","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/ajmg.c.30004","volume":"125","author":"Botto","year":"2004","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"10.1002\/bdra.20307-BIB4","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1136\/bmj.38336.664352.82","volume":"330","author":"Botto","year":"2005","journal-title":"BMJ"},{"key":"10.1002\/bdra.20307-BIB5","doi-asserted-by":"crossref","first-page":"774","DOI":"10.2105\/AJPH.2004.057760","volume":"96","author":"Botto","year":"2006","journal-title":"Am J Public Health"},{"key":"10.1002\/bdra.20307-BIB6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/j.1467-842X.2002.tb00908.x","volume":"26","author":"Bower","year":"2002","journal-title":"Aust NZJ Public Health"},{"key":"10.1002\/bdra.20307-BIB7","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.reprotox.2005.03.009","volume":"20","author":"Busby","year":"2005","journal-title":"Reprod Toxicol"},{"key":"10.1002\/bdra.20307-BIB8","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/bdra.20210","volume":"73","author":"Canfield","year":"2005","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1002\/bdra.20307-BIB9","first-page":"362","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1002\/bdra.20307-BIB10","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1056\/NEJM199212243272602","volume":"327","author":"Czeizel","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1002\/bdra.20307-BIB11","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF02390940","volume":"255","author":"Czeizel","year":"1994","journal-title":"Arch Gynecol Obstet"},{"key":"10.1002\/bdra.20307-BIB12","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1542\/peds.104.6.e66","volume":"104","author":"Czeizel","year":"1999","journal-title":"Pediatrics"},{"key":"10.1002\/bdra.20307-BIB13","doi-asserted-by":"crossref","first-page":"50","DOI":"10.7150\/ijms.1.50","volume":"1","author":"Czeizel","year":"2004","journal-title":"Int J Med Sci"},{"key":"10.1002\/bdra.20307-BIB14","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1002\/bdra.10124","volume":"67","author":"De Wals","year":"2003","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1002\/bdra.20307-BIB15","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1056\/NEJM200009283431314","volume":"343","author":"Halliday","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1002\/bdra.20307-BIB16","doi-asserted-by":"crossref","first-page":"2981","DOI":"10.1001\/jama.285.23.2981","volume":"285","author":"Honein","year":"2001","journal-title":"JAMA"},{"key":"10.1002\/bdra.20307-BIB17","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1080\/08035250500340396","volume":"94","author":"Klusmann","year":"2005","journal-title":"Acta Paediatr"},{"key":"10.1002\/bdra.20307-BIB18","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/ajmg.a.30651","volume":"135","author":"Lopez-Camelo","year":"2005","journal-title":"Am J Med Genet"},{"key":"10.1002\/bdra.20307-BIB19","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1002\/bdra.20075","volume":"70","author":"Mills","year":"2004","journal-title":"Birth Defects Res A Clin Mol Teratol"},{"key":"10.1002\/bdra.20307-BIB20","first-page":"200","volume":"14","author":"Moore","year":"2004","journal-title":"Epidemiology"},{"key":"10.1002\/bdra.20307-BIB21","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0140-6736(91)90133-A","volume":"338","year":"1991","journal-title":"Lancet"},{"key":"10.1002\/bdra.20307-BIB22","first-page":"241","volume":"167","author":"Persad","year":"2002","journal-title":"CMAJ"},{"key":"10.1002\/bdra.20307-BIB23","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.1016\/S0140-6736(02)11994-5","volume":"360","author":"Ray","year":"2002","journal-title":"Lancet"},{"key":"10.1002\/bdra.20307-BIB24","doi-asserted-by":"crossref","first-page":"s35","DOI":"10.1111\/j.1753-4887.2004.tb00072.x","volume":"62","author":"Ray","year":"2004","journal-title":"Nutr Rev"},{"key":"10.1002\/bdra.20307-BIB25","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1055\/s-2001-15925","volume":"63","author":"Rosch","year":"2001","journal-title":"Gesundheitswesen"},{"key":"10.1002\/bdra.20307-BIB26","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1016\/S0140-6736(01)07104-5","volume":"358","author":"Wald","year":"2001","journal-title":"Lancet"},{"key":"10.1002\/bdra.20307-BIB27","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1542\/peds.2005-0592","volume":"116","author":"Williams","year":"2005","journal-title":"Pediatrics"},{"key":"10.1002\/bdra.20307-BIB28","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1161\/CIRCULATIONAHA.105.570846","volume":"113","author":"Yang","year":"2006","journal-title":"Circulation"}],"container-title":["Birth Defects Research Part A: Clinical and Molecular Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdra.20307","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/bdra.20307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:22:16Z","timestamp":1625098936000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdra.20307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2006,10]]}},"URL":"https:\/\/doi.org\/10.1002\/bdra.20307","relation":{},"ISSN":["1542-0752","1542-0760"],"issn-type":[{"value":"1542-0752","type":"print"},{"value":"1542-0760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}