{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:57:43Z","timestamp":1790258263778,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,3,28]],"date-time":"2008-03-28T00:00:00Z","timestamp":1206662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>BACKGROUND:<\/jats:bold> <jats:italic>In utero<\/jats:italic> vascular disruptions are thought to be associated with a variety of birth defects. This study examined the descriptive epidemiology of several of those defects using data from a large birth defects registry. <jats:bold>METHODS:<\/jats:bold> Data on birth defects ascertained from pregnancies in 1996\u20132002 were obtained from the Texas Birth Defects Registry. Using Poisson regression, we calculated crude and adjusted associations between maternal and infant characteristics and birth defects thought to be related to vascular disruption. We repeated the analysis using isolated cases and cases occurring in mothers &lt;20 years. <jats:bold>RESULTS:<\/jats:bold> The most commonly shared pattern was observed for plurality and five defects: large intestinal atresia (PR 3.67; CI: 1.63\u20137.13), renal agenesis (PR 2.05; CI: 1.55\u20132.65), transverse limb deficiency (PR 1.85; CI: 1.28\u20132.57), porencephaly (PR 5.18; CI: 2.40\u20139.87), and Goldenhar syndrome (PR 3.45; CI: 1.04\u20138.53). Hispanics had the highest prevalence of gastroschisis (PR 1.21; CI: 1.05\u20131.40), transverse limb deficiency (PR 1.19; CI: 1.01\u20131.40), microtia\/anotia (PR 2.22; CI: 1.83\u20132.70), and Poland anomaly (PR 1.90; CI: 1.26\u20132.93). Male infants were at greatest risk for renal agenesis (PR 1.58; CI: 1.40\u20131.80), porencephaly (PR 1.66; CI: 1.03\u20132.72), and Poland anomaly (PR 1.52; CI: 1.05\u20132.21). <jats:bold>CONCLUSIONS:<\/jats:bold> Our study confirmed findings in previous studies, but also uncovered several new associations. Birth Defects Research (Part A), 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bdra.20449","type":"journal-article","created":{"date-parts":[[2008,3,29]],"date-time":"2008-03-29T04:03:21Z","timestamp":1206763401000},"page":"435-440","source":"Crossref","is-referenced-by-count":64,"title":["Descriptive epidemiologic features shared by birth defects thought to be related to vascular disruption in Texas, 1996\u20132002"],"prefix":"10.1002","volume":"82","author":[{"given":"Tasneem","family":"Husain","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Langlois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lowell E.","family":"Sever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Gambello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,6,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1994.02170070071014"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.85.5.710"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2003.12.017"},{"key":"e_1_2_6_5_1","first-page":"485","article-title":"Epidemiological study of intestinal atresias: central\u2010eastern France Registry 1976\u20131992","volume":"25","author":"Francannet C","year":"1996","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1542\/peds.73.4.467","article-title":"Congenital hydranencephaly\/porencephaly due to vascular disruption in monozygotic twins","volume":"73","author":"Jung JH","year":"1984","journal-title":"Pediatrics"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20238"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970331)69:3<237::AID-AJMG5>3.0.CO;2-I"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19970331)69:3<232::AID-AJMG3>3.0.CO;2-N"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.1998.00208.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.10129"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20042"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80261-8"},{"key":"e_1_2_6_15_1","first-page":"219","article-title":"Fetal vascular disruptions: mechanisms and some resulting birth defects","volume":"10","author":"Van Allen MI","year":"1981","journal-title":"Pediatric Ann"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.EDE.0000059226.36219.DE"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20114"}],"container-title":["Birth Defects Research Part A: Clinical and Molecular Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdra.20449","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdra.20449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T20:00:12Z","timestamp":1699992012000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdra.20449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1002\/bdra.20449"],"URL":"https:\/\/doi.org\/10.1002\/bdra.20449","archive":["Portico"],"relation":{},"ISSN":["1542-0752","1542-0760"],"issn-type":[{"value":"1542-0752","type":"print"},{"value":"1542-0760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6]]}}}