{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T17:12:45Z","timestamp":1758474765470},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T00:00:00Z","timestamp":1217462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Birth Defects Research"],"published-print":{"date-parts":[[2008,9]]},"abstract":"Abstract<\/jats:title>BACKGROUND:<\/jats:bold> In utero<\/jats:italic> exposure to carbimazole for maternal hyperthyroidism has been reported to cause choanal atresia. There are case reports of patent vitello\u2010intestinal duct and Meckel's diverticulum in similar association. CASE:<\/jats:bold> We report another such instance of an infant who was exposed to carbimazole in utero<\/jats:italic>, presenting with bilateral choanal atresia and patent vitello\u2010intestinal duct. CONCLUSIONS:<\/jats:bold> As there seems to be no reports of a possible association between propylthiouracil and congenital malformations, it may be safer to use propylthiouracil instead of carbimazole. Birth Defects Research (Part A), 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/bdra.20483","type":"journal-article","created":{"date-parts":[[2008,7,31]],"date-time":"2008-07-31T17:33:13Z","timestamp":1217525593000},"page":"649-652","source":"Crossref","is-referenced-by-count":16,"title":["Carbimazole embryopathy\u2010bilateral choanal atresia and patent vitello\u2010intestinal duct: A case report and review of literature"],"prefix":"10.1002","volume":"82","author":[{"given":"Lakshminarayanan","family":"Kannan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satish","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkat","family":"Kartikeyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neerja","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhulika","family":"Kabra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,31]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/ajmg.10458","article-title":"Choanal atresia: The result of maternal thyrotoxicosis or fetal carbimazole?","volume":"111","author":"Barwell J","journal-title":"Am J Med Genet"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19990305)83:1<43::AID-AJMG8>3.0.CO;2-C"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1096"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1072"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30418"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320280419"},{"key":"e_1_2_4_8_1","first-page":"A100","article-title":"Methimazole as a teratogenic etiology of choanal atresia\/multiple congenital anomaly syndrome","volume":"61","author":"Hall BD","year":"1997","journal-title":"Am J Hum Genet"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)63942-6"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-45-6-1187"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-8628(20001002)94:4<338::AID-AJMG13>3.0.CO;2-6"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420320221"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420050117"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.82.9.3099"},{"key":"e_1_2_4_15_1","first-page":"282","article-title":"Treatment of hyperthyroidism in pregnancy with propylthiouracil and methimazole","volume":"46","author":"Mujtaba Q","year":"1975","journal-title":"Obstet Gynecol"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2005.01046.x"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320130409"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320440216"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-106-1-60"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19980113)75:2<220::AID-AJMG21>3.0.CO;2-Q"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.9.1009"}],"container-title":["Birth Defects Research Part A: Clinical and Molecular Teratology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fbdra.20483","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/bdra.20483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T19:56:23Z","timestamp":1699991783000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/bdra.20483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,31]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2008,9]]}},"alternative-id":["10.1002\/bdra.20483"],"URL":"https:\/\/doi.org\/10.1002\/bdra.20483","archive":["Portico"],"relation":{},"ISSN":["1542-0752","1542-0760"],"issn-type":[{"value":"1542-0752","type":"print"},{"value":"1542-0760","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,31]]}}}